Results 221 to 230 of about 40,571 (376)

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

ACS Chem Biol [PDF]

While opto-genetics has proven to have tremendous value in revealing the functions of the macromolecular machinery in cells, it is not amenable to exploration of small molecules such as phospholipids (PLs).

core  

Erianin protects chondrocytes against IL-1β-induced oxidative stress and ferroptosis by activating GPX4/STING signaling in osteoarthritis. [PDF]

Inflamm Res
Li C, Jian W, Lu S, Wang Y, Fang C.
europepmc   +1 more source

Alginate Oligosaccharides Attenuate Ochratoxin A‐Induced Liver Injury through Regulating the Interaction of Nrf2 and NF‐κB Signaling Pathways

Food Frontiers, EarlyView.
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao, Xueqing Ye, Yan Guo, Zhongxiang Zhao, Qinghua Yao, Yaoyao Wang, Huimei Liu, Ziwei Lin, Wenchao Liu   +8 more
wiley   +1 more source

A Metal-responsive transcription factor-1 és a glutation peroxidáz család tagjait kódoló gének azonosítása és expressziójának jellemzése pontyban [PDF]

, 2010
Ferencz Ágnes
core  

SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer. [PDF]

Apoptosis
Zhong H, Chen R, Chen T, Lin M, Wen S, Zhang M, Liu D, Yu J, Chen J, Yi B, Liang R, Jiang W, Li Z.   +12 more
europepmc   +1 more source

LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure

Peipei Cheng, Xinting Wang, Qian Liu, Tianshu Yang, Enrui Dai, Wanjing Sha, Huiyan Qu, Hua Zhou   +7 more
openalex   +1 more source

Mn(II)‐Aloe‐Emodin Nanoscale Coordination Polymer Enhances Ferroptosis by Synergistically Enhancing Reactive Oxygen Species Generation via the Nrf2–GPX4 Axis [PDF]

Xiaoxin Yang, Chang Li, Mengjun Ge, Xiaoying Li, Wei Zhao, Guo Hu, Hemin Nie, Jun Liu   +7 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Ferroptosis inhibits cementoblast mineralization via cGAS-STING/GPX4 axis. [PDF]

Prog Orthod
Wei T, Li D, Zhang J, Zhou Z, Jiang C.
europepmc   +1 more source