Results 221 to 230 of about 29,098 (325)

Goat Milk‐Derived Extracellular Vesicles Attenuate Hydrogen Peroxide‐Treated Cell Damage in Human Skin Fibroblasts

Food Frontiers, EarlyView.
2 types of goat milk extracellular vesicles (GMEVs‐1 and GMEVs‐2) were investigated for their migration and skin permeation abilities in vitro and in vivo. Using an H2O2‐induced model in human skin fibroblasts cells, we demonstrated their protective effects of against oxidative stress, highlighting their potential for skin health applications ...
Chunping Chen, Youe Zhang, Peiran Li, Wenxu Zhou, Mo Chen, Baolong Liu, Caian He, Lin Han, Min Wang   +8 more
wiley   +1 more source

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

Glia, EarlyView.
Transcriptionally, P2RY12‐deficient microglia show heightened metabolic activity, iron handling, and oxidative stress at baseline. Upon LPS challenge, impaired glutathione antioxidant responses suggest increased vulnerability to ferroptosis. ABSTRACT Microglia are the resident immune cells of the CNS.
Aida Oryza Lopez‐Ortiz, Madison Doceti, JaQuinta Thomas, Abigayle Duffy, Morgan Coburn, Akhabue K. Okojie, Audrey Lee, Elizabeth Aidita Sou, Alban Gaultier, Ukpong B. Eyo   +9 more
wiley   +1 more source

HIF-1α alleviates ferroptosis in ulcerative colitis by regulation of GPX4. [PDF]

Cell Death Dis
Hu W, Cai Y, Cai D, Chen Z, Huang S, Zhang S, Zhuang H, Fang T, Chen X.   +8 more
europepmc   +1 more source

Uncovering SOD3 and GPX4 as new targets of Benzo[α]pyrene-induced hepatotoxicity through Metabolomics and Chemical Proteomics

, 2023
Yanwei Wang, Jiahui Zhao, Yipeng Xu, Cimin Tao, Jie Xin Tong, Yingjie Luo, Yong Chen, Xuesong Liu, Tengfei Xu   +8 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Long-Term Cigarette Smoke Exposure Promotes Neutrophil Ferroptosis Resistance, Inducing Neutrophil Extracellular Trap Formation and Driving Glucocorticoid Resistance in Chronic Obstructive Pulmonary Disease. [PDF]

Research (Wash D C)
Wang L, Zhu L, Tang Y, Wen Z, Peng L, Ci X.   +5 more
europepmc   +1 more source

A Metal-responsive transcription factor-1 és a glutation peroxidáz család tagjait kódoló gének azonosítása és expressziójának jellemzése pontyban [PDF]

, 2010
Ferencz Ágnes
core  

Resveratrol drives ferroptosis of acute myeloid leukemia cells through Hsa-miR-335-5p/NFS1/ GPX4 pathway in a ROS-dependent manner

, 2023
Jia Liu, Wei Gao, Yonghua Sheng, Jiafeng Sun, Donghu Wen   +4 more
openalex   +2 more sources

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

International Journal of Cancer, EarlyView.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti   +7 more
wiley   +1 more source

Alpha-linolenic acid protects against heatstroke-induced acute lung injury by inhibiting ferroptosis through Nrf2 activation. [PDF]

Redox Rep
Wang L, Ma J, Li Z, Zhao X, Chen Y, Wang P, Li Y, Chen Y, Yao X, Yao L, Li J.   +10 more
europepmc   +1 more source