ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang +3 more
wiley +1 more source
eGFP tagged ZnO nanoparticles from glioblastoma targeting ferroptosis and MRP1 in head and neck squamous cell carcinoma. [PDF]
Ali S +9 more
europepmc +1 more source
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint damage. Although ferroptosis has been implicated in RA progression, the role of disulfidptosis and its interaction with ferroptosis remains unclear.
Ting‐Ting Wang +10 more
wiley +1 more source
Ferroptosis-Based Nanotherapy for Pancreatic Ductal Adenocarcinoma Through Glutathione Depletion and Iron Accumulation. [PDF]
Yoon S +6 more
europepmc +1 more source
Effects of Ferrostatin‐1 on Vocal Folds in Aging Rats
Age‐related vocal fold degeneration is associated with oxidative stress, and ferroptosis may contribute to structural changes in aging vocal folds. In this aged rat model, intracordal injection of the antioxidant ferrostatin‐1 attenuated ferroptosis‐related changes and was associated with modulation of collagen accumulation, hyaluronic acid ...
Yong‐Il Cheon +8 more
wiley +1 more source
Protein Post-Translational Modifications in the Regulation of Ferroptosis: New Opportunities and Challenges for Cancer Immunotherapy. [PDF]
Xie X +8 more
europepmc +1 more source
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng +14 more
wiley +1 more source
Lapatinib suppresses cysteine deprivation-induced ferroptotic cell death by modulating mitochondrial function. [PDF]
Kim G +6 more
europepmc +1 more source
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
Mechanism of Ferroptosis in Cardiovascular Disease and Its Regulation by Natural Compounds: A Narrative Review. [PDF]
Pan R, Koo C, Sun S, Liu B, Ye X.
europepmc +1 more source

