Results 281 to 290 of about 40,571 (376)

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

open access: yesCell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie   +8 more
wiley   +1 more source

Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues

open access: yesCell Proliferation, EarlyView.
H1N1 infection during pregnancy specifically targets the fetal liver and lungs, triggering immune responses, tissue fibrosis and ferroptosis in parenchymal cells, ultimately leading to adverse pregnancy outcomes, offering insights into managing maternal H1N1 infections and their impact on fetal health.
Yuxi Jiang   +11 more
wiley   +1 more source

Ferroptosis in ischemia-reperfusion injury: molecular mechanisms and therapeutic strategies. [PDF]

open access: yesAm J Cardiovasc Dis
Wei YL   +9 more
europepmc   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

open access: yesCell Proliferation, EarlyView.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao   +8 more
wiley   +1 more source

Ferroptosis in Alzheimer's disease: molecular mechanisms and advances in therapeutic strategies. [PDF]

open access: yesFront Neurosci
Zhou Z   +9 more
europepmc   +1 more source

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