Results 101 to 110 of about 2,575,606 (330)

The Average Sentinel of the Heat Equation with an Unknown Reaction

Axioms
In this paper, we analyze the identification of the amount of pollutant discharged problem by each source in a heat system when the dynamics of the state are governed by a parameterized unknown operator.
Houria Selatnia, Abdelhamid Ayadi, Imad Rezzoug   +2 more
doaj   +1 more source

Model Reduction using a Frequency-Limited H2-Cost

, 2012
We propose a method for model reduction on a given frequency range, without the use of input and output filter weights. The method uses a nonlinear optimization approach to minimize a frequency limited H2 like cost function.
Löfberg, Johan, Petersson, Daniel
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gradient type optimization methods for electronic structure calculations [PDF]

, 2013
Xin Zhang, Jinwei Zhu, Zaiwen Wen, Aihui Zhou   +3 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Sparse identification of Lagrangian for nonlinear dynamical systems via proximal gradient method. [PDF]

Sci Rep, 2023
Purnomo A, Hayashibe M.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Antimicrobial Susceptibility Testing to Erythromycin and Azithromycin of Clinical Isolates of Bordetella pertussis Circulating in Russia

Эпидемиология и вакцинопрофилактика
Relevance. Antibacterial drugs are widely used to treat and prevent infections of the upper and lower respiratory tract. The large-scale and unjustified use of antimicrobials to treat these infections has led to the emergence of resistance in most ...
A. S. Pimenova, N. T. Gadua, I. Yu. Andrievskaya, O. Yu. Borisova, M. S. Petrova, A. B. Borisova, S. S. Afanas'ev, I. V. Podoprigora, M. S. Afanas'ev, T. I. Moskvina, G. V. Vorob'eva, I. M. Degtyareva, O. V. Timirkina, S. A. Luk'yanceva, T. N. Trigorlova   +14 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Angiographic velocimetry analysis using contrast dilution gradient method with a 1000 frames per second photon-counting detector. [PDF]

J Med Imaging (Bellingham), 2023
Williams KA, Shields A, Setlur Nagesh SV, Chudzik M, Bednarek DR, Rudin S, Ionita C.   +6 more
europepmc   +1 more source