Results 81 to 90 of about 1,684,530 (333)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Blending arts and sciences: gimmick or necessity? [PDF]
, 2008 The shortage of degree qualified engineers in the UK is well documented. On the other hand the surplus of art and design graduates is growing. Whilst acknowledging the shortage in engineering graduates, there is also the need to recognise the breadth and
Bradley, Michael D. +2 more
core
Higher education funding reforms in England : the distributional effects and the shifting balance of costs [PDF]
, 2007 This paper undertakes a quantitative analysis of substantial reforms to the system of higher education (HE) finance first announced in 2004 and then revised again in July 2007. The reforms introduced deferred fees for HE, payable by graduates through the
Dearden, Lorraine +3 more
core +3 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
BTTN Journal, 2022 Foreign policy conduct of a State, executed by its leaders, broadly reflects various patterns of its experiences, beliefs and policies. Domestic factors coupled with systemic pressures play an important role in shaping states’ behavior.
Adeela Azam
doaj
Student Debt and the Class of 2007 [PDF]
, 2008 Analyzes state-by-state trends in the average debt of 2007 graduates and percentages of graduates with debt. Lists high- and low-debt states and campuses.
Matthew Reed
core
International Medical Graduates in the US Physician Workforce
The Journal of the American Osteopathic Association, 2015 International medical graduates (IMGs) play a vital role in the US health care system. These graduates represent 26% of physicians in practice and 24% of residents in specialty programs.
P. Ranasinghe
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Prepared for Practice? Exploring and Evaluating the First Six Months of Post-qualified Practice in Social Work [PDF]
, 2009 This project explores how effective the Social work degree has been in enabling graduates to feel prepared for the practice of social work. Quantitative and qualitative data from online questionnaires and interviews with twelve graduates revealed that ...
Cooper, Barry +3 more
core
Knowledge sharing implementation and job searching in Malaysia [PDF]
, 2009 The aim of this research is to integrate analysis through case studies on how knowledge sharing could be implemented successfully. Furthermore, this study also will clarify a conceptualisation that provides a new understanding of the relationship ...
Burke, ME, Sulainman, N
core +1 more source