Results 131 to 140 of about 1,098,781 (385)
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang +4 more
wiley +1 more source
ACCELERATED SKIN GRAFT REJECTION IN HUMANS PRE-IMMUNIZED WITH HOMOLOGOUS PERIPHERAL LEUKOCYTES* [PDF]
Eli A. Friedman +4 more
openalex +1 more source
The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells
Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang +6 more
wiley +1 more source
Use of OKT3 with ciclosporin and steroids for reversal of acute kidney and liver allograft rejection [PDF]
OKT3 monoclonal antibody therapy was added to preexisting baseline immunosuppressive treatment with ciclosporin and steroids to treat rejection in 52 recipients of cadaveric livers and 10 recipients of cadaveric kidneys.
Demetris, AJ, Fung, JJ, Porter, KA
core +1 more source
Reticular Frameworks for Advanced Polymer Materials
Reticular frameworks (RFs) such as metal–organic frameworks, covalent organic frameworks, and hydrogen‐bonded organic frameworks offer versatile platforms for polymer materials innovation, enabling regulated polymerization, efficient macromolecular purification, and polymer functionalization.
Bohan Cheng +2 more
wiley +1 more source
Introduction: Cytomegalovirus (CMV) infection is mainly associated with acute or chronic graft rejection in various solid organs. This study was conducted with the aim of evaluating the plasma viral load of CMV infection in postheart transplant patients ...
Kambiz Mozaffari +6 more
doaj +1 more source
HISTOPATHOLOGICAL AND HISTOCHEMICAL ALTERATIONS IN THE EARLY STAGES OF CORNEAL GRAFT REJECTION [PDF]
Frank M. Polack
openalex +1 more source
Biomarkers for corneal graft rejection? [PDF]
Despite the many developments in immunosuppressive therapy, corneal graft rejection still is the leading cause for graft failure.1 This clinical scenario is a constant headache for ophthalmologists that regularly perform corneal transplants. Often long-term systemic immunosuppression is required with the undesirable consequences from systemic steroids ...
openaire +2 more sources
Citrate‐Enhanced PCL Scaffolds for Bone Tissue Engineering
This study investigates citrate‐enhanced polycaprolactone (PCL) scaffolds designed for bone tissue engineering. Utilizing 3D printing technology, four scaffold patterns (triple hexagon, grid, gyroid, zigzag) are evaluated for mechanical properties, cellular proliferation, osteogenic differentiation, and gene expression.
Muge Musmula +6 more
wiley +1 more source
IMMUNOLOGICAL PARADOXES: THEORETICAL CONSIDERATIONS IN THE REJECTION OR RETENTION OF GRAFTS, TUMORS, AND NORMAL TISSUE [PDF]
Jonas Salk
openalex +1 more source

