Results 131 to 140 of about 1,018,561 (360)

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Clinical profile and outcomes of rejection after deep anterior lamellar keratoplasty in keratoconus

Indian Journal of Ophthalmology
Purpose: To report the clinical features and management outcomes of rejection after deep anterior lamellar keratoplasty (DALK). Methods: The clinical features, indications, predisposing risk factors, management, and outcome of six eyes of six patients ...
Priyanka Sudaboina, Sunita Chaurasia, Somasheila Murthy   +2 more
doaj   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

Advanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng, Ruizeng Luo, Ying Chen, Xiaoqiang Liu, Yuanyin Xi, Muhammad Usman, Xupin Jiang, Zhou Li, Jiaping Zhang   +8 more
wiley   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Determinant Factors in Graft Rejection Using Cox Regression, among the Recipients of Second Renal Transplant in Imam Khomeini Hospital in Urmia, 1988-2000

Iranian South Medical Journal, 2010
Background: The objective of this study was to evaluate graft survival among the recipients of second renal transplant in Imam Khomeini centre hospital in Urmia. Methods: The study population consisted of 50 patients receiving renal grafts for the second
Rahim Tahmasebi, Anoushirvan Kazemnejad, Ali Taghizadeh Afshari, Farzad Eskandari, Soghrat Faghih zadeh   +4 more
doaj  

The role of macrophage lineage cells in kidney graft rejection and survival.

Transplantation, 2012
Large numbers of macrophage lineage cells are present in transplants undergoing ischemia-reperfusion injury and rejection, and their presence correlates with a high probability of rejection.
A. Rowshani, Elly J. F. Vereyken
semanticscholar   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Corneal allograft rejection: Risk factors, diagnosis, prevention, and treatment

Indian Journal of Ophthalmology, 1999
Recent advances in corneal graft technology, including donor tissue retrieval, storage and surgical techniques, have greatly improved the clinical outcome of corneal grafts.
Dua Harminder, Azuara-Blanco Augusto
doaj  

Diagnosis and treatment of acute antibody-mediated rejection in renal transplant: the role of C4d and donor-specific antibody identification [PDF]

Einstein (São Paulo), 2009
Objective: To evaluate the incidence of antibody-mediated rejection after the C4d  and  donor specific antibody  detection was provided by Luminex in renal transplantation biopsies; to compare acute antibody-mediated  rejection characteristics as related
Lúcio Roberto Requião Moura, Margareth Afonso Torres, Eduardo José Tonato, Érika Ferraz de Arruda, Eric Roger Wroclawski, Maurício Fregonesi Rodrigues da Silva, Denise Maria Avancine Costa Malheiros, Marcelino de Souza Durão, Alvaro Pacheco-Silva   +8 more
doaj