Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling
Advanced Science, EarlyView.This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu +6 more
wiley +1 more source
Graft Copolymers of Maleic Anhydride and Its Isostructural Analogues: High Performance Engineering Materials [PDF]
arXiv, 2011 This review summarizes the main advances published over the last 15 years outlining the different methods of grafting, including reactive extruder systems, surface modification, grafting and graft copolymerization of synthetic and natural polymers with maleic anhydride and its isostructural analogues such as maleimides and maleates, and anhydrides ...
arxiv
HISTOPATHOLOGICAL AND HISTOCHEMICAL ALTERATIONS IN THE EARLY STAGES OF CORNEAL GRAFT REJECTION [PDF]
, 1962 Frank M. Polack
openalex +1 more source
Gastroenterology, 2011 Transplantation of organs between genetically different individuals of the same species causes a T cell-mediated immune response that, if left unchecked, results in rejection and graft destruction.
A. Sánchez‐Fueyo, T. Strom
semanticscholar +1 more source
Biomarkers for corneal graft rejection? [PDF]
Eye, 2009 Despite the many developments in immunosuppressive therapy, corneal graft rejection still is the leading cause for graft failure.1 This clinical scenario is a constant headache for ophthalmologists that regularly perform corneal transplants. Often long-term systemic immunosuppression is required with the undesirable consequences from systemic steroids ...
openaire +2 more sources
Imaging follow-up after liver transplantation [PDF]
, 2016 Liver transplantation (LT) represents the best treatment for end-stage chronic liver disease, acute liver failure and early stages of hepatocellular carcinoma.
ANZIDEI, MICHELE +7 more
core +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
Advanced Science, EarlyView.This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim +12 more
wiley +1 more source
Risk factors for Pneumocystis jirovecii pneumonia (PJP) in kidney transplantation recipients
Scientific Reports, 2017 Pneumocystis jirovecii pneumonia (PJP) is a potentially life-threatening infection that occurs in immunocompromised patients. The aim of this study was to evaluate risk factors for PJP in kidney transplantation recipients.
Su Hwan Lee +11 more
doaj +1 more source
ACCELERATED SKIN GRAFT REJECTION IN HUMANS PRE-IMMUNIZED WITH HOMOLOGOUS PERIPHERAL LEUKOCYTES* [PDF]
, 1961 Eli A. Friedman +4 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source