Results 101 to 110 of about 425,098 (322)

Progress in the Development of Effective Vaccines to Prevent Selected Gram-Positive Bacterial Infections [PDF]

open access: yesThe American Journal of the Medical Sciences, 2010
Infections caused by virulent Gram-positive bacteria, such as Staphylococcus aureus, group B streptococci and group A streptococci, remain significant causes of morbidity and mortality despite progress in antimicrobial therapy. Despite significant advances in the understanding of the pathogenesis of infection caused by these organisms, there are only ...
Michael S, Bronze, James B, Dale
openaire   +2 more sources

Characterization and Antimicrobial Activity of Hafnium Nanostructures Fabricated by Physical Vapor Deposition Through a Colloidal Mask

open access: yesAdvanced Materials Interfaces, EarlyView.
We generate hafnium nanostructures by first depositing polystyrene particles of varying diameter followed by physical vapour deposition of hafnium thin films. The resultant structure shows a kill‐on‐contact effect against both Gram‐negative Escherichia coli and Gram‐positive Staphylococcus aureus.
Andrew Boden   +6 more
wiley   +1 more source

Preliminary Analysis of the Anti-biofilm Efficacy of Manuka Honey on Extended Spectrum Β-lactamase Producing Escherichia Coli Tem-3 and Klebsiella Pneumoniae Shv18, Associated with Urinary Tract Infections [PDF]

open access: yes, 2019
open access articleUrinary Tract Infections (UTIs) are one of the most common infections in the UK and many other parts of the world. The prevalence of the Extended Spectrum β-Lactamases (ESBLs) producing UTIs, combined with their ability to form a bio ...
Baho, S.   +2 more
core  

Outcomes and predictors of early infection after heart transplantation [PDF]

open access: yes, 2018
Background: Limited data exist on the incidence and outcome of early infection after orthotopic heart transplantation (OHT). The purpose of this study was to describe characteristics and outcomes of OHT recipients with an early infection and to identify ...
Balsara, Keki   +6 more
core   +2 more sources

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li   +7 more
wiley   +1 more source

Parental transfer of the antimicrobial protein LBP/BPI protects Biomphalaria glabrata eggs against oomycete infections [PDF]

open access: yes, 2013
Copyright: © 2013 Baron et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
A Baeza Garcia   +75 more
core   +8 more sources

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Emerging Therapies for Serious Gram-Positive Bacterial Infections: A Focus on Linezolid [PDF]

open access: yesClinical Infectious Diseases, 2000
Respiratory tract infections and skin and soft-tissue infections frequently are caused by gram-positive cocci, and treating these infections with standard antibiotics has recently become problematic. Many of the primary pathogens causing these infections are now resistant to current standard treatment regimens.
openaire   +2 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

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