Results 71 to 80 of about 6,661,076 (287)

Emerging Therapies for Serious Gram-Positive Bacterial Infections: A Focus on Linezolid [PDF]

Clinical Infectious Diseases, 2000
Respiratory tract infections and skin and soft-tissue infections frequently are caused by gram-positive cocci, and treating these infections with standard antibiotics has recently become problematic. Many of the primary pathogens causing these infections are now resistant to current standard treatment regimens.
openaire   +2 more sources

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

Advanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai, Shuhong Wang, Chenguang Ding, Xenia Kostoulias, Anton P. Le Brun, Hsien‐Yi Hsu, Jhih‐Hang Jiang, Yajun Wang, Richard A. Strugnell, Anton Y. Peleg, Hsin‐Hui Shen   +10 more
wiley   +1 more source

Phenotypic and Genotypic Detection of Staphylococcus aureus and Escherichia coli in Subclinical Mastitis Goat Milk in Lumajang, Indonesia

Jurnal Medik Veteriner
This study aimed to identify the Staphylococcus aureus and Escherichia coli bacteria that cause subclinical mastitis in dairy goats in the Senduro sub-district of Lumajang regency, Indonesia.
Himmatul Khasanah, Nalendra Gigih Wibawanto Putra, Nanang Tri Hariyadi, Nur Widodo, Desy Widianingrum, Roni Yulianto, Joseph F. Dela Cruz, Nurul Pratiwi   +7 more
doaj   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Group A Streptococcus, 2019 [PDF]

Citation: Centers for Disease Control and Prevention. 2019. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group A Streptococcus, 2019.

core  

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

A PGRPLC1/Rel2-F axis controls Anopheles gambiae resistance to systemic infections with Gram-positive bacteria containing Lys-type peptidoglycan.

PLoS Pathogens
In the Afrotropical malaria vector Anopheles gambiae s.l., the Imd pathway plays pleiotropic roles in immunity, including resistance to malaria parasites, that are mediated by its NF-κB transcription factor Rel2. Rel2 exists as a full-length form (Rel2-F)
Amani Audi, Suheir Zeineddine, Sana Jaber, Mike A Osta   +3 more
doaj   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance [PDF]

Science Translational Medicine
Several antibiotic candidates are in development against Gram-positive bacterial pathogens, but their long-term utility is unclear. To investigate this issue, we studied the laboratory evolution of resistance to antibiotics that have not yet reached the market.
Martins, Ana, Judák, Fanni, Farkas, Zoltán, Szili, Petra, Grézal, Gábor, Csörgő, Bálint, Czikkely, Márton Simon, Maharramov, Elvin, Daruka, Lejla, Spohn, Réka, Balogh, Dávid, Daraba, Andreea, Juhász, Szilvia, Vágvölgyi, Máté, Hunyadi, Attila, Cao, Yihui, Sun, Zhenquan, Li, Xuechen, Papp, Balázs, Pál, Csaba   +19 more
openaire   +3 more sources

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Haemophilus influenzae, 2020 [PDF]

Dataset version: Jul 2022; Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Haemophilus influenzae, 2020.

core  

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source