Results 51 to 60 of about 4,412,822 (263)

Single Deletion Unmasks Hidden Anti-Gram-Negative Bacterial Activity of an Insect Defensin-Derived Peptide

open access: yes
Insect defensins are a large family of antimicrobial peptides primarily active against Gram-positive bacteria. Here, we explore their hidden anti-Gram-negative bacterial potential via a nature-guided strategy inspired by natural deletion variants of ...
Shunyi Zhu (183597)   +2 more
core   +2 more sources

Antimicrobial potential of Streptomyces sp. to the Gram positive and Gram negative pathogens

open access: yesJournal of Infection and Public Health, 2019
Background: The occurrence of drug resistant infectious disease causing microbial pathogens was highly spreaded because of the wide level application of the commercially available antimicrobial agents.
Mysoon Al-Ansari   +3 more
doaj   +1 more source

Grevillea juncifolia Hook. and Grevillea robusta A. Cunn. Ex. R. Br. Methanolic Leaf and Flower Extracts Inhibit the Growth of Gram Positive and Gram Negative Bacteria

open access: yes, 2019
Introduction: The development of multi-antibiotic resistant strains of bacteria has necessitated the search for new effective antibacterial therapies. Several Grevillea spp.
Cock, Ian Edwin
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

ANTIBACTERIAL ACTIVITY OF PIPER CUBEBA LINN. FRUIT EXTRACTS AGAINST SELECTED BACTERIAL PATHOGENS IN BASRAH CITY [PDF]

open access: yesBasrah Journal of Veterinary Research, 2013
ﺺﻠﺨﺘﺴﻣ ﻲﻫﻭ (Piper cubeba) ﺔﺑﺎﺒﻜﻟﺍ ﺕﺎﺒﻧ ﺭﺎﻤﺜﻟ ﺕﺎﺼﻠﺨﺘﺴﻣ ﺔﻌﺑﺭﺃ ﺮﻴﻀﺤﺗ ﻢﺗ ﺔﺳﺍﺭﺪﻟﺍ ﻩﺬﻫ ﻲﻓ ﻩﺬﻫ ﻪﻳﻮﺘﺤﺗ ﺎﻣ ﻦﻋ ﻒﺸﻜﻟﺍ ﻢﺗ .ﺔﻴﻜﻴﻧﺎﻜﻴﻤﻟﺍ ﺔﺑﺍﺫﻹﺍ ﺔﻘﻳﺮﻄﺑ ﺩﺭﺎﺑ ﻲﺋﺎﻣﻭ ﻲﻣﺭﻮﻓﺭﻮﻠﻛﻭ ﻲﻧﻮﺘﻴﺳﺍﻭ ﻲﻟﻮﺤﻛ ﻮﻤﻧ ﻂﻴﺒﺜﺗ ﻲﻓ ﺕﺎﺼﻠﺨﺘﺴﻤﻟﺍ ﻩﺬﻬﻟ ﺔﻳﺮﻴﺘﻜﺑ ﺪﻀﻟﺍ ﺔﻴﻟﺎﻌﻔﻟﺍ ﺭﺎﺒﺘﺧﺍ ﻢﺗ ﻚﻟﺫ ﺪﻌﺑ ﺔﻴﺋﺎﻴﻤﻴﻛ
Tamadher M. K. Al-Tememy
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Gram Negative Bacterial Toe Web Intertrigo [PDF]

open access: yesEuropean Medical Journal Dermatology, 2014
Gram-negative infection of the toe web space is less frequent than dermatophytes and yeasts, but it is more challenging, especially with the involvement of Pseudomonas aeruginosa in relation to antibiotic resistance and the increased risk of ...
Laura Atzori   +3 more
doaj  

Callistemon linearis Schrad. and J.C. Wendl. Extracts Inhibit the Growth of Gram-Positive Bacteria but have no Effect on Gram Negative Bacteria

open access: yes, 2019
Introduction: The development of multi-antibiotic resistant strains of bacteria has necessitated the search for new effective antibacterial therapies. Many Callistemon spp.
Cock, Ian Edwin   +2 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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