Results 111 to 120 of about 102,482 (316)

Seesaw induced Higgs Mechanism

open access: yes, 2002
We discuss a two scalar doublets model which induces the Higgs mechanism by means of a seesaw mechanism. This model naturally predicts a light Higgs scalar whose mass is suppressed by the grand unification scale.
Calmet, X.
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Self-Similar Symmetry Model and Cosmic Microwave Background

open access: yesFrontiers in Applied Mathematics and Statistics, 2016
In this paper, we present the self-similar symmetry (SSS) model that describes the hierarchical structure of the universe. The model is based on the concept of self-similarity, which explains the symmetry of the cosmic microwave background (CMB).
Tomohide eSonoda
doaj   +1 more source

Standard Grand Unification from Superstrings

open access: yes, 1995
Recent developments about the construction of standard $SO(10)$ and $SU(5)$ grand unified theories from 4-dimensional superstrings are presented. Explicit techniques involving higher level affine Lie algebras, for obtaining such stringGUTs from symmetric
Aldazabal, Gerardo
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Standard Model quark/lepton masses and the Cabibbo-Kobayashi-Maskawa mixing in an SU(8) theory

open access: yesJournal of High Energy Physics
The observed Standard Model (SM) quark/lepton mass hierarchies and the Cabibbo-Kobayashi-Maskawa (CKM) mixing pattern are described in an SU(8) theory through its realistic symmetry breaking pattern with three intermediate stages, which rely on a set of ...
Ning Chen, Ying-nan Mao, Zhaolong Teng
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Towards Grand Unification

open access: yes
Sidharth had shown that gravitation can be reconciled with electromagnetic and other forces if we start from a Landau-Ginzburg phase transition. This is further remarked upon and a unification of all forces of nature is proposed.Comment: 10 pages, IIAMIS-
Sidharth, Burra G.
core  

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