Results 91 to 100 of about 759,547 (247)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Supersymmetry with Grand Unification
, 1993 Supersymmetry (SUSY) has many well known attractions, especially in the context of Grand Unified Theories (GUTs). SUSY stabilizes scalar mass corrections (the hierarchy problem), greatly reduces the number of free parameters, facilitates gauge coupling ...
Barger, V +3 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Supersymmetry and grand unification [PDF]
, 1995 Supersymmetry and Grand Unification are the two most promising directions for physics beyond the Standard Model. They receive indirect experimental support from the apparent lightness of the Higgs boson, the values of the gauge couplings measured at LEP ...
Ellis, John R.
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The global B − L symmetry in the flavor-unified SU(N) theories
Journal of High Energy PhysicsWe study the origin of the global B − L symmetry in a class of flavor-unified theories with gauge groups of SU(N ≥ 6). In particular, we focus on the SU(8) theory which can minimally embed three-generational SM fermions non-trivially.
Ning Chen, Ying-nan Mao, Zhaolong Teng
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Implications of supersymmetric SU(15) grand unification
, 1993 We consider the supersymmetric version of the grand unification scheme based on SU(15). We apply the constraints on the coupling constants form the LEP data and require the coupling constants to be less than one.
Sarkar, Uptal, Brahmachari, Biswajoy
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Linear Higher-Order Pre-Unification
, 2018 We develop a pre-unification algorithm in the style of Huet for the linear lambda-calculus lambda-> -o & T which includes intuitionistic functions (->), linear functions (-o), additive pairing (&), and additive unit (T).
Frank Pfenning (5356877) +1 more
core +1 more source