Results 71 to 80 of about 102,001 (282)

Electroweak flavour unification

Journal of High Energy Physics, 2022
We propose that the electroweak and flavour quantum numbers of the Standard Model (SM) could be unified at high energies in an SU(4) × Sp(6) L × Sp(6) R anomaly-free gauge model. All the SM fermions are packaged into two fundamental fields, Ψ L ∼ (4 , 6 ,
Joe Davighi, Joseph Tooby-Smith
doaj   +1 more source

Proton decay and grand unification

, 2009
I review the theoretical and experimental status of proton decay theory and experiment. Regarding theory, I focus mostly, but not only, on grand unification.
Senjanovic, Goran
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Weinberg angle and 5D RGE effects in a SO(11) GUT theory

Physics Letters B, 2020
The Weinberg angle is an important parameter in Grand Unified Theories (GUT) as its size is crucially influenced by the assumption of unification. In scenarios with different steps of symmetry breaking, in particular in models that involve gauge-Higgs ...
Christoph Englert, David J. Miller, Dumitru Dan Smaranda   +2 more
doaj   +1 more source

Anatomy of scalar mediated proton decays in SO(10) models

Journal of High Energy Physics, 2022
Realistic models based on the renormalizable grand unified theories have varieties of scalars, many of which are capable of mediating baryon (B) and lepton (L) number non-conserving processes.
Ketan M. Patel, Saurabh K. Shukla
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Predictive power of grand unification from quantum gravity

Journal of High Energy Physics, 2020
If a grand-unified extension of the asymptotically safe Reuter fixed-point for quantum gravity exists, it determines free parameters of the grand-unified scalar potential. All quartic couplings take their fixed-point values in the trans-Planckian regime.
Astrid Eichhorn, Aaron Held, Christof Wetterich   +2 more
doaj   +1 more source

Probing minimal grand unification through gravitational waves, proton decay, and fermion masses

Journal of High Energy Physics, 2023
Motivated by the direct discovery of gravitational waves (GWs) from black holes and neutron stars, there is a growing interest in investigating GWs from other sources.
Shaikh Saad
doaj   +1 more source

Non-Canonical Gauge Coupling Unification in High-Scale Supersymmetry Breaking

, 2005
The string landscape suggests that the supersymmetry breaking scale can be high, and then the simplest low energy effective theory is the Standard Model (SM).
Allahverdi, Altarelli, Amaldi, Anchordoqui, Antoniadis, Arason, Arkani-Hamed, Arkani-Hamed, Arkani-Hamed, Arkani-Hamed, Arkani-Hamed, Arvanitaki, Arvanitaki, Asaka, Azzi, Babu, Babu, Bajc, Barger, Barger, Barger, Barger, Beneke, Bethke, Binger, Blumenhagen, Bousso, Calmet, Camara, Carena, Chang, Chankowski, Chen, Chen, Cheng, Cheng, Cheung, Cheung, Chun, Conlon, Csaki, Cvetic, Datta, Davoudiasl, Demir, Denef, Denef, Deshpande, Diaz, Dienes, Dienes, Dine, Dine, Dixon, Dixon, Donoghue, Donoghue, Douglas, Douglas, Drees, Dutta, Dvali, Eidelman, Ellis, Font, Frampton, Frampton, Froggatt, Gabadadze, Georgi, Giddings, Giryavets, Giudice, Giudice, Gogoladze, Green, Green, Green, Gupta, Haba, Haber, Hagiwara, Hall, Hebecker, Hewett, Hill, Huang, Huitu, Ibarra, Jing Jiang, Kachru, Kane, Kasuya, Kawamura, Kilian, Kim, Kokorelis, Kors, Langacker, Langacker, Langacker, Li, Li, Li, Li, Machacek, Machacek, Machacek, Mahbubani, Marcus, Martin, Martin, Masiero, Mukhopadhyaya, Murayama, Nandi, Paul Langacker, Peccei, Peccei, Pierce, Profumo, Raffelt, Rizzo, Sarkar, Scherk, Schuster, Senatore, Silverstein, Susskind, Susskind, Thomas, Tianjun Li, Toharia, Turner, V. Barger, Weinberg, Zhu   +136 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source