Results 61 to 70 of about 704,450 (240)

Gauge coupling unification in gauge-Higgs GUT: theory and phenomenology

Journal of High Energy Physics
We present a concise survey of the running of gauge couplings in realistic models of gauge-Higgs grand unification in a slice of AdS5 space and investigate their potential unification. Besides unifying the gauge groups of the Standard Model, these models
Andrei Angelescu, Andreas Bally, Florian Goertz, Sascha Weber   +3 more
doaj   +1 more source

Yukawa unification with four Higgs doublets in supersymmetric GUT

Physics Letters B, 2019
We discuss the Yukawa coupling unification, which can emerge in the grand unified theory, in the context of scenarios with more than one pair of Higgs doublet since the current LHC constraint has become a problem for the Yukawa unification scenarios with
Bhaskar Dutta, Yukihiro Mimura
doaj   +1 more source

Supersymmetry and supergravity: Phenomenology and grand unification [PDF]

, 1993
A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local ...
Nath, P., Arnowitt, R.
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The Weinberg angle and 5D RGE effects in a SO(11) GUT theory

Physics Letters B, 2020
The Weinberg angle is an important parameter in Grand Unified Theories (GUT) as its size is crucially influenced by the assumption of unification. In scenarios with different steps of symmetry breaking, in particular in models that involve gauge-Higgs ...
Christoph Englert, David J. Miller, Dumitru Dan Smaranda   +2 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Tri-unification: a separate SU(5) for each fermion family

Journal of High Energy Physics
In this paper we discuss SU(5)3 with cyclic symmetry as a possible grand unified theory (GUT). The basic idea of such a tri-unification is that there is a separate SU(5) for each fermion family, with the light Higgs doublet(s) arising from the third ...
Mario Fernández Navarro, Stephen F. King, Avelino Vicente   +2 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Implications of a dark grand unification

Journal of High Energy Physics
Given that dark matter and normal matter are nontrivially unified in a grand unified theory, called dark grand unification, we derive novel residual theories at low energy explaining dark matter and neutrino mass.
Phung Van Dong, Do Thi Huong
doaj   +1 more source

Predictive power of grand unification from quantum gravity

Journal of High Energy Physics, 2020
If a grand-unified extension of the asymptotically safe Reuter fixed-point for quantum gravity exists, it determines free parameters of the grand-unified scalar potential. All quartic couplings take their fixed-point values in the trans-Planckian regime.
Astrid Eichhorn, Aaron Held, Christof Wetterich   +2 more
doaj   +1 more source