Results 41 to 50 of about 1,383 (257)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Supersymmetric grand unification
, 2008 After a brief discussion of motivations and prototype models, we review recent studies of model building and of proton decay in supersymmetric grand unification. A new effect is mentioned for ΔB ≠ 0 four-scalar interactions induced by an intermediate scale (1010 ∼ 1012 GeV) supersymmetry breaking.
openaire +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Probing grand unification with quantum sensors
Physics Letters BWe discuss how grand unification can be probed with experiments at low energies using quantum sensors. Specifically, we show that scalar multiplets coupled to the gauge sector of a grand unified theory provide a mechanism for a time-varying unified ...
Xavier Calmet, Nathaniel Sherrill
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Warped supersymmetric grand unification [PDF]
Physical Review D, 2003 41 pages, LaTeX, version to appear in Phys.
Goldberger, Walter D. +2 more
openaire +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Seeing higher-dimensional grand unification in primordial non-gaussianities
Journal of High Energy Physics, 2019 The observed low-energy values of the SU(3) × SU(2) × U(1) gauge couplings, extrapolated via the minimal Standard Model Renormalization Group evolution, hint at the exciting possibility of a Grand Unified Theory (GUT) at M U ∼ 1014 GeV — a scale, however,
Soubhik Kumar, Raman Sundrum
doaj +1 more source
Nilpotent symmetries as a mechanism for Grand Unification
Journal of High Energy Physics, 2021 In the classic Coleman-Mandula no-go theorem which prohibits the unification of internal and spacetime symmetries, the assumption of the existence of a positive definite invariant scalar product on the Lie algebra of the internal group is essential.
Lars Andersson +2 more
doaj +1 more source
Grand unification of the sterile neutrino [PDF]
Physics Letters B, 1998 5 pages, Revtex; Typos in the values of parameters in the table ...
Brahmachari, Biswajoy +1 more
openaire +2 more sources