Results 41 to 50 of about 704,450 (240)
Fermion masses and mixings in supersymmetric SO(10) with third-generation quasi-Yukawa unification
Journal of High Energy PhysicsWe discuss the charged and neutral fermion masses and mixings in a supersymmetric SO(10) model with a minimal Higgs sector consisting of the multiplets 10 H , 45 H , and $${16}_{H}+{\overline{16} }_{H}$$ .
Shaikh Saad, Qaisar Shafi
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Neutrino masses, δ PMNS, and m ββ in SO(10)
Journal of High Energy PhysicsWe explore the leptonic sector of a recently proposed supersymmetric SO(10) model with supersymmetry breaking in the 3–10 TeV range. A new ingredient in this work is the requirement that the observed baryon asymmetry is explained via non-thermal ...
Shaikh Saad, Qaisar Shafi
doaj +1 more source
Supersymmetric grand unification
, 1982 Supersymmetry (SUSY) has many well known attractions, especially in the context of Grand Unified Theories (GUTs). SUSY stabilizes scalar mass corrections (the hierarchy problem), greatly reduces the number of free parameters, facilitates gauge coupling ...
Ellis, Jonathan Richard +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Grand Unification Signal from Ultrahigh Energy Cosmic Rays? [PDF]
, 2001 The spectrum of ultrahigh energy (above approximate to 10(9) GeV) cosmic rays is consistent with the decay of grand unification scale particles. The predicted mass is m(x) = 10(h) GeV, where h = 14.6(-1.7)(+1.6)
Z. Fodor, S. D. Katz, Fodor, Z, Katz, SD
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Flavor tests of grand unification [PDF]
, 1995 How will we ever be convinced that grand unification, or string theory, or some other physics at very high energies, is correct? Two ways in which this could happen are: The structure of the theory is itself so compelling and tightly constrained, and the
Hall, L J, Hall, L. J., Hall, L.J.
core
Implications of supersymmetric SU(15) grand unification
, 1993 We consider the supersymmetric version of the grand unification scheme based on SU(15). We apply the constraints on the coupling constants form the LEP data and require the coupling constants to be less than one.
Sarkar, Uptal, Brahmachari, Biswajoy
core +1 more source