Results 91 to 100 of about 210,813 (335)
Gravitational Waves and Proton Decay: Complementary Windows into Grand Unified Theories [PDF]
, 2021 Stephen F. King +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
GUT origins of general electroweak multiplets and their oblique parameters
Nuclear Physics BWe survey the scalar electroweak multiplets that can originate from a grand unified theory (GUT) like SU(5), SO(10) or E6. We compute the oblique parameters S, T and U for a general scalar electroweak multiplet and then apply the results to the ...
Liang Chen +4 more
doaj +1 more source
, 2006 22 pages, 18 figures, Invited talk given at the 2nd World Summit on Physics Beyond the Standard Model, Galapagos Islands, Ecuador, June 22-25 ...
openaire +2 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Grand Unification and Light Color-Octet Scalars at the LHC
, 2008 We study the properties and production mechanisms of color-octet scalars at the LHC. We focus on the single production of both charged and neutral members of an (8,2)_1/2 doublet through bottom quark initial states. These channels provide a window to the
Gavin, Ryan +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
ReligionsThis article utilizes canonical interpretation to reassess Paul’s eulogy in Ephesians 1:3–14 by situating it within the Bible’s overarching narrative of placemaking—from Genesis to Revelation. Rejecting purely historical-grammatical approaches, the study
David Wayne Larsen
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Five golden rules for superstring phenomenology
, 2004 Recent measurements of the values of gauge coupling constants as well as neutrino properties support the idea of a grand unified (GUT) description of particle physics at a large scale of $M_{GUT}\sim 10^{16}$ GeV.
Nilles, Hans Peter
core +1 more source