Results 1 to 10 of about 70,906 (218)

Granulocyte-macrophage colony-stimulating factor for newly diagnosed glioblastoma [PDF]

Neoplasia: An International Journal for Oncology Research
Background: There is a clear need to improve the efficiency of therapeutic strategy for patients with newly diagnosed glioblastoma (GBM). The purpose of this study was to evaluate the feasibility of hypofractionated intensity-modulated radiation therapy (
Caineng Cao, Le Wang, Feng Jiang, Qifeng Jin, Ting Jin, Shuang Huang, Qiaoying Hu, Yuanyuan Chen, Yongfeng Piao, Yonghong Hua, Xinglai Feng, Yi Zhou, Xiaozhong Chen   +12 more
doaj   +2 more sources

Distinct osteoclastogenic potential of granulocyte-macrophage colony-stimulating factor-induced monocyte subsets [PDF]

Bone Reports
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and progressive bone destruction. Although osteoclasts mediate bone resorption in RA, recent evidence suggests that inflammatory osteoclasts ...
Shiho Kinoshita, Yasuhiro Omata, Kojiro Sato   +2 more
doaj   +2 more sources

Disseminated Cryptococcal Gattii infection in a patient with anti-granulocyte-macrophage colony-stimulating-factor autoantibody: a case report [PDF]

BMC Infectious Diseases
Background Cryptococcosis is an opportunistic fungal infection in immunocompromised patients. The major species include Cryptococcus grubii, Cryptococcus neoformans, and rarely, Cryptococcus gattii.
Chi-Tung Chen, Mao-Wang Ho, Wei-Hsin Chung   +2 more
doaj   +2 more sources

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR [PDF]

Drugs of the Future, 1989
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a well-characterized hematopoietic growth factor. Recently, using purified recombinant-derived material, we have found that GM-CSF is also a potent activator of mature functional macrophages.
H.-G. Klingemann, H.J. Deeg
  +6 more sources

Encapsulation of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in liposomes prepared by thin film hydration and their transfer to mesenchymal stem cells and cord blood hematopoietic stem cells

Archives of Medical Science, 2020
Introduction Cytokines are important immune modulator factors controlling homeostasis of the body and are involved in tissue regeneration after wound healing.
Sławomir Lewicki, Monika Leśniak, Agnieszka Sobolewska-Ruta, Aneta Lewicka, Marta Grodzik, Eugeniusz K. Machaj, Marek Saracyn, Jacek Z. Kubiak, Zygmunt Pojda   +8 more
doaj   +1 more source

Immunomodulatory properties of recombinant human granulocyte-macrophage colony-stimulating factor

Медицинская иммунология, 2023
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a myelopoietic growth factor that exerts pleiotropic effect not only on the differentiation of immature progenitor cells into polymorphonuclear neutrophils, monocytes/macrophages and dendritic ...
G. M. Sysoeva, S. G. Gamaley, T. I. Esina, E. D. Danilenko   +3 more
doaj   +1 more source

Induction of type II collagen expression in M2 macrophages derived from peripheral blood mononuclear cells

Scientific Reports, 2022
The human type II collagen (Col II), specifically expressed in chondrocytes, is a crucial component of the adult hyaline cartilage. We examine the potential of artificial induction of Col II in human peripheral blood mononuclear cells (PBMNCs) as a novel
Fu-Hui Wang, Chia-Ying Hsieh, Ching-I. Shen, Chang-Han Chuang, Yu-Hsuan Chung, Chi-Chung Kuo, Kuan-Der Lee, Chih-Lung Lin, Hong-Lin Su   +8 more
doaj   +1 more source

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors

FEBS Open Bio, 2022
There are two types of abnormal hematopoiesis in solid tumor occurrence and treatment: pathological hematopoiesis, and myelosuppression induced by radiotherapy and chemotherapy. In this review we primarily focus on the abnormal pathological hematopoietic
Kai He, Xi Liu, Robert D. Hoffman, Rong‐Zhen Shi, Gui‐Yuan Lv, Jian‐Li Gao   +5 more
doaj   +1 more source

Study on Hemostimulating Properties of Granulocyte-Macrophage Colony Stimulating Factor

Биопрепараты: Профилактика, диагностика, лечение, 2020
The hemostimulating properties of granulocyte-macrophage colony-stimulating factor (GM-CSF) make possible its clinical use in alleviating side effects of anti-cancer radio- and chemotherapy, in bone marrow transplantation, and in the treatment of some ...
G. G. Shimina, A. V. Bateneva, S. G. Gamaley, T. I. Esina, T. G. Tereshchenko, E. D. Danilenko   +5 more
doaj   +1 more source

Failure of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in a patient with Kostmann syndrome

The Turkish Journal of Pediatrics, 1999
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar, Hakan Ongun, M. Akif Yeşilipek, Olcay Yeğin   +3 more
doaj   +1 more source