Results 11 to 20 of about 73,182 (298)

Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes

Tumor Biology, 2017
Granulocyte-macrophage colony-stimulating factor has been widely used as an adjuvant therapy for cancer patients exhibiting myelosuppression induced by chemotherapy or radiotherapy. However, the effects of granulocyte-macrophage colony-stimulating factor
Qiaowei Zheng, Xueqian Li, Xiaoliang Cheng, Ting Cui, Yingcheng Zhuo, Wenbin Ma, Xue Zhao, Peipei Zhao, Xuanlin Liu, Weiyi Feng   +9 more
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Granulocyte-macrophage colony-stimulating factor receptor expression in clinical pain disorder tissues and role in neuronal sensitization

PAIN Reports, 2018
. Introduction:. Granulocyte-macrophage colony-stimulating factor receptor (GM-CSFR) is highly expressed in peripheral macrophages and microglia, and is involved in arthritis and cancer pain in animal models.
Philippe Donatien, Uma Anand, Yiangos Yiangou, Marco Sinisi, Michael Fox, Anthony MacQuillan, Tom Quick, Yuri E. Korchev, Praveen Anand   +8 more
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Cryptococcus tetragattii Meningitis Associated with Travel, Taiwan

Emerging Infectious Diseases, 2023
Meningitis caused by Cryptococcus tetragattii fungus is rare and has been found in specific geographic regions. We report a case of meningitis caused by C. tetragattii (molecular type VGIV) in an immunocompetent patient in Taiwan.
Pin-Han Wu, Chih-Hao Chen, Yu-Tzu Lin, Yu Ao, Kuo-Hsi Lin, Wen-Hsin Hsih, Chia-Huei Chou, Chih-Yu Chi, Mao-Wang Ho, Po-Ren Hsueh   +9 more
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The Potential Role of Recombinant Hematopoietic Colony-Stimulating Factors in Preventing Infections in the Immunocompromised Host

Canadian Journal of Infectious Diseases, 1991
Hematopoietic colony-stimulating factors coordinate the proliferation and maturation of bone marrow and peripheral blood cells during normal hematopoiesis.
James Rusthoven
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Myeloid Colony Stimulating Factors as Regulators of Macrophage Polarization

Frontiers in Immunology, 2014
The scope of functional heterogeneity in macrophages has been defined by two polarized end states known as M1 and M2, which exhibit the pro-inflammatory activities necessary for host defense and the tissue repair activities required for tissue repair ...
Thomas A Hamilton
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Modeling the Hematopoietic Landscape

Frontiers in Cell and Developmental Biology, 2019
Some time ago, we proposed a continuum-like view of the lineages open to hematopoietic stem cells (HSCs); each HSC self-renews or chooses from the spectrum of all end-cell options and can then “merely” differentiate.
Geoffrey Brown, Rhodri Ceredig
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High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Frontiers in Cell and Developmental Biology, 2021
Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies.
Di Cui, Alexandra Franz, Sophie A. Fillon, Linda Jannetti, Timo Isambert, Katrin Fundel-Clemens, Heinrich J. Huber, Coralie Viollet, Alexander Ghanem, Akira Niwa, Bernd Weigle, Stefan Pflanz, Stefan Pflanz   +12 more
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Distinct macrophage phenotypes skewed by local granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis

Clinical & Translational Immunology, 2020
Objective To determine the presence and spatial distribution of different macrophage phenotypes, governed by granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) skewing signals, in giant cell ...
William F Jiemy, Yannick vanSleen, Kornelis SM van derGeest, Hilde A tenBerge, Wayel H Abdulahad, Maria Sandovici, Annemieke MH Boots, Peter Heeringa, Elisabeth Brouwer   +8 more
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AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
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