Results 221 to 230 of about 73,182 (298)

Significance of Platinum‐Based Chemotherapy With Programmed Death‐1 Blockade in Limited Disease Small Cell Lung Cancer: A Retrospective Study

Thoracic Cancer, Volume 16, Issue 13, July 2025.
The median progression‐free survival and overall survival periods were 5.9 (95% CI, 4.7–7.3) and 24.9 (95% CI, 16.8–28.1) months, respectively. Chemoimmunotherapy is an effective treatment for recurrent disease after chemoradiotherapy in patients with limited disease small cell lung cancer.
Ayako Shiono, Hisao Imai, Kyoichi Kaira, Takanori Abe, Yuki Sato, Ken Yamamoto, Hiroki Watanabe, Yuko Tsuchiya‐Kawano, Akihiro Tamiya, Takashi Osaki, Noriko Yanagitani, Shigeru Tanzawa, Toshiyuki Sumi, Kohei Yoshimine, Yohei Matsui, Satoshi Endo, Kazuhiko Shibata, Shinnosuke Takemoto, Yosuke Miura, Yoshiaki Nagai, Junichi Nakagawa, Takeshi Tsuda, Hiroshi Kagamu   +22 more
wiley   +1 more source

Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines. [PDF]

Mol Autism
Takada R, Toritsuka M, Yamauchi T, Ishida R, Kayashima Y, Nishi Y, Ishikawa M, Yamamuro K, Ikehara M, Komori T, Noriyama Y, Kamikawa K, Saito Y, Okano H, Makinodan M.   +14 more
europepmc   +1 more source

Extracellular Vesicles miRNome Profiling Reveals miRNAs Engagement in Dysfunctional Lipid Metabolism, Chronic Inflammation and Liver Damage in Subjects With Metabolic Dysfunction‐Associated Steatotic Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 1, Page 22-32, July 2025.
This study explores the association between the miRNome profile of circulating extracellular vesicles and metabolic dysfunction, liver inflammation, and damage in patients with metabolic MASLD, identifying key miRNAs (miR‐122‐5p, miR‐375‐3p, let‐7d‐5p, and let‐7f‐5p) that modulate lipid metabolism and inflammatory pathways in ‘at‐risk MASH’ patients ...
Gian Paolo Caviglia, Elisabetta Casalone, Chiara Rosso, Serena Aneli, Alessandra Allione, Fabrizia Carli, Cristina Grange, Angelo Armandi, Chiara Catalano, Giovanni Birolo, Beatrice Foglia, Davide Giuseppe Ribaldone, Amalia Gastaldelli, Giuseppe Matullo, Elisabetta Bugianesi   +14 more
wiley   +1 more source

NF-kappa B as inducible transcriptional activator of the granulocyte-macrophage colony-stimulating factor gene.

, 1990
Ralf Schreck, Patrick A. Baeuerle
openalex   +1 more source

Inflammation and response to bacterial infection as potential drivers of equine odontoclastic tooth resorption and hypercementosis: A proteomics insight

Equine Veterinary Journal, Volume 57, Issue 4, Page 977-990, July 2025.
Abstract Background Equine dental diseases significantly impact a horse's overall health, performance and quality of life. They can result in secondary infections and digestive disturbances, potentially leading to colic. A recently described disease affecting the incisors of horses is equine odontoclastic tooth resorption and hypercementosis (EOTRH ...
Anders Jensen, Emily J. Clarke, Zoe Nugent, Emily Paice, Iris Gringel, Kazuhiro Yamamoto, Guido Rocchigiani, Andrew J. Peffers, Lee Cooper, Mandy J. Peffers   +9 more
wiley   +1 more source

Phase II trial of vaccination with autologous, irradiated melanoma cells engineered by adenoviral mediated gene transfer to secrete granulocyte-macrophage colony stimulating factor in patients with stage III and IV melanoma. [PDF]

Front Oncol
Sussman TA, Severgnini M, Giobbie-Hurder A, Friedlander P, Swanson SJ, Jaklitsch M, Clancy T, Goguen LA, Lautz D, Swanson R, Daley H, Ritz J, Dranoff G, Hodi FS.   +13 more
europepmc   +1 more source

Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes--those for GM-CSF, interleukin-4 (IL-4), and IL-5.

, 1991
Shoichiro Miyatake, Joseph Shlomai, Ken‐ichi Arai, Naoko Arai   +3 more
openalex   +1 more source

JCMM Annual Review on Advances in Biotechnology for the Treatment of Haematological Malignancies: A Review of the Latest In‐Patient Developments 2024–2025

Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT Advances in biotechnology are set to revolutionise the treatment of haematological malignancies. Current treatments have limited efficacy due to their high toxicity and poor long‐term outcomes, particularly in acute myeloid leukaemia (AML). In 2024–2025, emerging targeted therapies promise improved results with reduced adverse effects.
Akbar M. Shahid, William Vainchenker, Stefan N. Constantinescu   +2 more
wiley   +1 more source

A Mendelian randomization study on the causal association of circulating cytokines with diabetic nephropathy

Journal of Diabetes Investigation, Volume 16, Issue 7, Page 1274-1283, July 2025.
We performed a two‐sample MR analysis to investigate the causal relationship between circulating cytokines and DN in individuals of European ancestry. We found evidence to support the causal role of genetically predicted circulating levels on the increased risk of DN, including interferon‐gamma, stem cell factor, and stromal‐cell‐derived factor 1 alpha,
Yiming Xu, Tian Xiao, Junqing Yang, Jiali Wang, Bingting Wang, Chen Qiao   +5 more
wiley   +1 more source

Immunosenescence and Inflammaging in Dogs and Cats: A Narrative Review

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A consistent and important feature of biological aging is the change in the types and functions of cells comprising the immune system. Across various mammalian species, this change follows consistent patterns, including diminished protective capacity, leading to increased vulnerability to infectious disease, and increased low‐grade chronic ...
Brennen A. McKenzie
wiley   +1 more source