Results 21 to 30 of about 70,906 (218)

Distinct macrophage phenotypes skewed by local granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis

Clinical & Translational Immunology, 2020
Objective To determine the presence and spatial distribution of different macrophage phenotypes, governed by granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) skewing signals, in giant cell ...
William F Jiemy, Yannick vanSleen, Kornelis SM van derGeest, Hilde A tenBerge, Wayel H Abdulahad, Maria Sandovici, Annemieke MH Boots, Peter Heeringa, Elisabeth Brouwer   +8 more
doaj   +1 more source

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj   +1 more source

Single‐Cell Mechanical Characterization of Human Macrophages

Advanced NanoBiomed Research, 2022
Macrophages remodel their mechanics during differentiation toward different subtypes and drastically adapt their shapes during phagocytosis or entry to inflamed tissues.
Tom M. J. Evers, Vahid Sheikhhassani, Huaqi Tang, Mariëlle C. Haks, Tom H. M. Ottenhoff, Alireza Mashaghi   +5 more
doaj   +1 more source

Application of Western Blot for detection of neutrophil apoptosis-related proteins

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The aim of this study was to evaluate suitability of using Western Blot for detection of neutrophil apo­pto­sis and neutrophil apoptosis-related proteins, respectively. Neutrophils were isolated from blood of healthy adult donors and incubated with G-CSF
Petr Sláma
doaj   +1 more source

Saharan dust induces the lung disease-related cytokines granulocyte–macrophage colony-stimulating factor and granulocyte colony-stimulating factor

Environment International
Desert dust exposure is associated with adverse respiratory health effects. Desert dust is a complex pollutant mixtures that includes respirable crystalline and amorphous particles, metals, and microbial constituents.
Gerrit Bredeck, Jochen Dobner, Andrea Rossi, Roel P.F. Schins   +3 more
doaj   +1 more source

Factores de Crescimento Hematopoiético

Revista Portuguesa de Pneumologia, 1995
SUMÁRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguíneas.
Maria De Fátima Miguel Rodrigues, Margarida Cristóvão, Agostinho Costa, M.a José Melo   +3 more
doaj   +1 more source

Granulocyte macrophage colony stimulating factor (GM-CSF) biological actions on human dermal fibroblasts

European Journal of Histochemistry, 2009
Fibroblasts are involved in all pathologies characterized by increased ExtraCellularMatrix synthesis, from wound healing to fibrosis. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a cytokine isolated as an hemopoietic growth factor but ...
S Montagnani, L Postiglione, G Giordano-Lanza, F Di Meglio, C Castaldo, S Sciorio, N Montuori, G Di Spigna, P Ladogana, A Oriente, G Rossi   +10 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Cloning and eukaryotic expression of chicken granulocyte macrophage colony stimulating factor gene

浙江大学学报. 农业与生命科学版, 2009
In order to study the biological characteristics of chicken granulocyte macrophage colony stimulating factor (GM-CSF), Sichuan shandi black-bone chicken GM-CSF was amplified from ConA stimulated peripheral blood lymphocytes using RT-PCR.
TAN Bing, WANG Hong-ning, ZHANG Yi, FAN Wen-qiao   +3 more
doaj   +1 more source

Predictive Diagnosis of Breast Cancer Based on Cytokine Profile

Engineering Proceedings, 2023
A predictive model for the early diagnosis of breast cancer based on the concentration of some cytokines in the tumor microenvironment in the blood was built in this paper.
Marina Barulina, Yuliya Gergenreter, Natalia Zakharova, Vladimir Maslyakov, Vladimir Fedorov, Ivan Ulitin   +5 more
doaj   +1 more source