Fibroblasts are involved in all pathologies characterized by increased ExtraCellularMatrix synthesis, from wound healing to fibrosis. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a cytokine isolated as an hemopoietic growth factor but ...
S Montagnani +10 more
doaj +1 more source
Predictive Diagnosis of Breast Cancer Based on Cytokine Profile
A predictive model for the early diagnosis of breast cancer based on the concentration of some cytokines in the tumor microenvironment in the blood was built in this paper.
Marina Barulina +5 more
doaj +1 more source
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano +6 more
core
Cloning and eukaryotic expression of chicken granulocyte macrophage colony stimulating factor gene
In order to study the biological characteristics of chicken granulocyte macrophage colony stimulating factor (GM-CSF), Sichuan shandi black-bone chicken GM-CSF was amplified from ConA stimulated peripheral blood lymphocytes using RT-PCR.
TAN Bing +3 more
doaj +1 more source
Diospyrin is a bisnaphthoquinonoid medicinal compound derived from Diospyros lotus, with known anti-cancer, anti-tubercular, and anti-leishmanial activities against Leishmania donovani.
Adnan Shahidullah +7 more
doaj +1 more source
Use of recombinant human granulocyte-macrophage colony stimulating factor in an infant with reticular dysgenesis [PDF]
We present the case of a 2-month-old infant with reticular dysgenesis who was treated with recombinant granulocyte-macrophage colony stimulating factor with the aim of stimulating granulopoiesis while awaiting bone marrow ...
Alzina, V. (Valentín) +4 more
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Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources
Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]
The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther +23 more
core +2 more sources
Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80(dim), CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients [PDF]
We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that are deficient in cell surface expression of the costimulatory molecules B7-1 (CD8O) and
Angus W. Thomson +48 more
core +1 more source
Therapy options in pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis is a rare condition characterized by the accumulation of lipoproteinaceous material within the airspaces, resulting in impaired gas transfer, and clinical manifestations ranging from asymptomatic to severe respiratory ...
Maurizio Luisetti +5 more
doaj +1 more source

