OCT‐2 Is Associated With Pro‐Metastatic Epigenomic Properties of Triple‐Negative Breast Cancer Cells
Cancer Science, EarlyView.The transcription factor OCT‐2 (encoded by POU2F2) is involved in the formation of super‐enhancers (SEs) in triple‐negative breast cancer (TNBC) cells. Overexpression of POU2F2 enhances the metastasis of TNBC cells in mice, and their expression is highly correlated to the poor prognosis of TNBC patients. ABSTRACT Triple‐negative breast cancer (TNBC) is
Kazuki Ogikubo +7 more
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Granulocyte colony-stimulating factor-producing cutaneous squamous cell carcinoma: A case report and literature review. [PDF]
Medicine (Baltimore)Ishiguro A +3 more
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Clonal Hematopoiesis and Solid Cancers
Cancer Science, EarlyView.This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen +3 more
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Effects of different granulocyte colony stimulating factor regimens on patients with euploid embryo transfer in recurrent implantation failure. [PDF]
Front Med (Lausanne)Karaosmanoglu O +6 more
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Granulocyte-macrophage colony-stimulating factor produced by splenic T lymphocytes of mice infected with Schistosoma japonicum [PDF]
, 1986 Makoto Owhashi, Yukifumi Nawa
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Cancer Science, EarlyView.Tumor‐associated neutrophils (TANs) enhance STAT3 phosphorylation by upregulating aquaporin 9 (AQP9) to promote breast cancer (BC) progression. AQP9 may be crucial for TAN‐mediated BC progression and is a novel target for immunotherapy in patients with BC.
Wuqin Xu +5 more
wiley +1 more source
Role of granulocyte colony stimulating factor in the treatment of cirrhosis of liver: a systematic review. [PDF]
J Int Med Res, 2023 Rajpurohit S +4 more
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Granulocyte-macrophage colony-stimulating factor induces the expression of the CD11b surface adhesion molecule on human granulocytes in vivo [PDF]
, 1988 MA Socinski +6 more
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Cancer Science, EarlyView.This study developed a genetically engineered and transplantable cholangiocarcinoma (CCA) organoid model in immunocompetent mice to investigate the role of tumor‐infiltrating immune cells in CCA progression. The findings revealed that tumor‐infiltrating neutrophils (TINs) exhibit antitumor activity by directly killing cancer cells through reactive ...
Osamu Sugahara +6 more
wiley +1 more source