Results 11 to 20 of about 189,801 (353)

Granulocyte colony-stimulating factor and leukemogenesis [PDF]

open access: yesMediators of Inflammation, 2004
THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are ...
Lorena Lobo de Figueiredo   +2 more
doaj   +4 more sources

Failure of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in a patient with Kostmann syndrome

open access: yesThe Turkish Journal of Pediatrics, 1999
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar   +3 more
doaj   +3 more sources

Granulocyte colony-stimulating factor [PDF]

open access: yesCanadian Medical Association Journal, 2006
[Drs. Shyu, Lin and Li respond:] Following the guidelines on using G-CSF for stem cell mobilization,[1][1] we carefully adjusted the dose of G-CSF (15 μg/kg) for up to 5 days to avoid the leukocyte numbers rising above 70 × 109/L (in fact, the leukocyte count for all patients was below 61.3 ×
Cengiz Beyan   +2 more
  +9 more sources

Favorable response to pembrolizumab in granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma

open access: yesIJU Case Reports, 2022
Introduction Granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma is rare, with a poor prognosis. Advanced urothelial carcinoma is currently treated with immune checkpoint inhibitors, whose efficacy for granulocyte ...
Hiroki Takeda   +9 more
doaj   +1 more source

The discovery of angiogenic growth factors: the contribution of Italian scientists [PDF]

open access: yes, 2014
Angiogenesis is regulated, under both physiological and pathological conditions, by numerous “non-classic” pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF),
Domenico Ribatti
core   +1 more source

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

open access: yesJournal of the American College of Cardiology, 2005
Two studies in this issue of the Journal report the effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) to promote coronary neovascularization; both were stopped early because of ominous results. In the report by Zbinden et al. ([1][
Robert F. Wilson, Timothy D. Henry
openaire   +2 more sources

Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes

open access: yesTumor Biology, 2017
Granulocyte-macrophage colony-stimulating factor has been widely used as an adjuvant therapy for cancer patients exhibiting myelosuppression induced by chemotherapy or radiotherapy. However, the effects of granulocyte-macrophage colony-stimulating factor
Qiaowei Zheng   +9 more
doaj   +1 more source

The Potential Role of Recombinant Hematopoietic Colony-Stimulating Factors in Preventing Infections in the Immunocompromised Host

open access: yesCanadian Journal of Infectious Diseases, 1991
Hematopoietic colony-stimulating factors coordinate the proliferation and maturation of bone marrow and peripheral blood cells during normal hematopoiesis.
James Rusthoven
doaj   +1 more source

Granulocyte colony-stimulating factor and its receptor [PDF]

open access: yesBlood, 1991
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein of Mr of about 20,000, which stimulates proliferation and differentiation of progenitor cells of neutrophils. Recent clinical application of G-CSF has proven that this hormone is effective in treatment of patients suffering from neutropenia.
James D. Griffin, George D. Demetri
openaire   +6 more sources

Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells

open access: yesHaematologica, 2012
Background Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell ...
Fabio Di Giacomo   +6 more
doaj   +1 more source

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