Results 11 to 20 of about 189,801 (353)
Granulocyte colony-stimulating factor and leukemogenesis [PDF]
THE granulocyte colony-stimulating factor (G-CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are ...
Lorena Lobo de Figueiredo +2 more
doaj +4 more sources
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar +3 more
doaj +3 more sources
Granulocyte colony-stimulating factor [PDF]
[Drs. Shyu, Lin and Li respond:] Following the guidelines on using G-CSF for stem cell mobilization,[1][1] we carefully adjusted the dose of G-CSF (15 μg/kg) for up to 5 days to avoid the leukocyte numbers rising above 70 × 109/L (in fact, the leukocyte count for all patients was below 61.3 ×
Cengiz Beyan +2 more
+9 more sources
Introduction Granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma is rare, with a poor prognosis. Advanced urothelial carcinoma is currently treated with immune checkpoint inhibitors, whose efficacy for granulocyte ...
Hiroki Takeda +9 more
doaj +1 more source
The discovery of angiogenic growth factors: the contribution of Italian scientists [PDF]
Angiogenesis is regulated, under both physiological and pathological conditions, by numerous “non-classic” pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF),
Domenico Ribatti
core +1 more source
Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor
Two studies in this issue of the Journal report the effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) to promote coronary neovascularization; both were stopped early because of ominous results. In the report by Zbinden et al. ([1][
Robert F. Wilson, Timothy D. Henry
openaire +2 more sources
Granulocyte-macrophage colony-stimulating factor has been widely used as an adjuvant therapy for cancer patients exhibiting myelosuppression induced by chemotherapy or radiotherapy. However, the effects of granulocyte-macrophage colony-stimulating factor
Qiaowei Zheng +9 more
doaj +1 more source
Hematopoietic colony-stimulating factors coordinate the proliferation and maturation of bone marrow and peripheral blood cells during normal hematopoiesis.
James Rusthoven
doaj +1 more source
Granulocyte colony-stimulating factor and its receptor [PDF]
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein of Mr of about 20,000, which stimulates proliferation and differentiation of progenitor cells of neutrophils. Recent clinical application of G-CSF has proven that this hormone is effective in treatment of patients suffering from neutropenia.
James D. Griffin, George D. Demetri
openaire +6 more sources
Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells
Background Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell ...
Fabio Di Giacomo +6 more
doaj +1 more source

