ABSTRACT Objectives The understanding of usefulness of immunoglobulin replacement therapy (IgRT) for hypogammaglobulinemia (HGG) in patients with hematologic malignancies (HM) has changed over time. This is mainly caused by the introduction of new treatment, such as B‐cell targeted agents.
Keichiro Mihara+5 more
wiley +1 more source
The impact of post-remission granulocyte colony-stimulating factor use in the phase 3 studies of venetoclax combination treatments in patients with newly diagnosed acute myeloid leukemia. [PDF]
DiNardo CD+14 more
europepmc +1 more source
Maternal Immune Activation During Pregnancy and Obstetric Outcomes: A Population‐Based Cohort Study
ABSTRACT Objective Maternal immune activation has been proposed as a mechanism for adverse pregnancy outcomes, yet the mechanisms and effects of timing remain unclear. Immune disruption in early gestation may be particularly detrimental as this is an important period for placental development, which has been associated with the pathology of adverse ...
Frederieke A. J. Gigase+10 more
wiley +1 more source
The granulocyte colony-stimulating factor produced during Streptococcus suis infection controls neutrophil recruitment in the blood without affecting bacterial clearance. [PDF]
Bleuzé M+4 more
europepmc +1 more source
The study aimed to determine the optimal timing and duration of filgrastim administration for the primary prevention of febrile neutropenia (FN) in breast cancer patients undergoing adjuvant TAC chemotherapy. Our findings suggest that initiating daily filgrastim from Day 2 and continuing for 7 days optimizes toxicity reduction.
Zisun Kim+7 more
wiley +1 more source
Daratumumab improved severe neutrophilia and paraneoplastic bone marrow fibrosis in granulocyte-colony stimulating factor-producing multiple myeloma. [PDF]
Sakamoto M+8 more
europepmc +1 more source
A single‐centre retrospectively analyzed 37 BRPC/LAPC patients receiving neoadjuvant chemotherapy ± chemoradiotherapy. Surgical resection was feasible in 62% of patients, with 38% of patients achieving R0 resections. The median overall survival was 21 months, and disease‐free survival was 12.7 months.
Avtaj Nerwal+5 more
wiley +1 more source
Granulocyte colony-stimulating factor in neutropenia management after CAR-T cell therapy: A safety and efficacy evaluation in refractory/relapsed B-cell acute lymphoblastic leukemia. [PDF]
Cao X+17 more
europepmc +1 more source