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Clinical applications of granulocyte-colony stimulating factor

Frontiers in Bioscience, 2007
Granulocyte colony stimulating factor (G-CSF) is a naturally occurring potent neutrophil growth factor. Recombinant human G-CSF has been developed by pharmaceutical companies, and since the late 1980's, multiple clinical trials have explored its efficacy in a variety of medical conditions.
Lillian Sung, Yigal Dror
openaire   +3 more sources

Mutagenesis of human granulocyte colony stimulating factor

Biochemical and Biophysical Research Communications, 1989
To define the structure-function relationship, we have made a number of mutants of human granulocyte colony-stimulating factor (hG-CSF) by in vitro mutagenesis. The results indicate that most of the mutations located in the internal and C-terminal regions of the molecule abolished the activity, whereas the mutants without N-terminal 4, 5, 7, or 11 ...
Seiga Itoh   +11 more
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Impurities in Granulocyte Colony-Stimulating Factor?

Archives of Dermatology, 1994
The case presented by Samlaska and Noyes 1 in the May 1993 issue of theArchivesof a patient who developed pruritus and erythematous edematous plaques at granulocyte colony-stimulating factor (G-CSF) injection sites is very interesting and unique with regard to the authors' conjecture at possible causation.
openaire   +2 more sources

Neuroprotective Effect of Granulocyte-Colony Stimulating Factor

Frontiers in Bioscience, 2007
Granulocyte-colony stimulating factor (G-CSF) is a growth factor which stimulates proliferation, differentiation, and survival of hematopoietic progenitor cells. G-CSF is being used extensively in clinical practice to accelerate recovery of patients from neutropenia after cytotoxic therapy.
Jadhav, John H. Zhang, Ihsan Solaroglu
openaire   +3 more sources

The Granulocyte-Macrophage Colony-Stimulating Factors [PDF]

open access: possible, 1986
Haemopoiesis is the process whereby a small population of multipotential stem cells continuously gives rise to a large number of mature blood cells which comprise eight distinct cellular lineages. In normal health, the circulating levels of mature cells are remarkably invariant, suggesting that their production is tightly regulated.
openaire   +1 more source

Granulocyte-Macrophage Colony-Stimulating Factor

Journal of Pediatric Oncology Nursing, 1991
Donna L. Betcher, Nora Burnham
openaire   +2 more sources

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

Nature, 2008
Robert T Wheeler   +2 more
exaly  

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