Results 1 to 10 of about 953 (126)

Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual. [PDF]

Cureus, 2021
We present a case of rapidly progressive granulomatous amoebic encephalitis caused by Balamuthia mandrillaris in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy.
Paudel AC, Patel N, Quang J, Casella C, Sigal A, Parajuli P, Oladunjoye O, Oke IO, Khanal S, Bhattarai K.   +9 more
europepmc   +4 more sources

Mitochondrial genome diversity of Balamuthia mandrillaris revealed by a fatal case of granulomatous amoebic encephalitis. [PDF]

Front Microbiol, 2023
IntroductionBalamuthia (B.) mandrillaris is a free-living amoeba that can cause rare yet fatal granulomatous amoebic encephalitis (GAE). However, efficacious treatment for GAE is currently unavailable, especially when genomic studies on B. mandrillaris are limited.MethodsIn this study, B.
Law CT, Nivesvivat T, Xiong Q, Kulkeaw K, Shi L, Ruenchit P, Suwanpakdee D, Suwanpakdee P, Tongkrajang N, Sarasombath PT, Tsui SK.   +10 more
europepmc   +4 more sources

A patient with granulomatous amoebic encephalitis caused by Balamuthia mandrillaris survived with two excisions and medication. [PDF]

BMC Infect Dis, 2022
Abstract Background Granulomatous amoebic encephalitis (GAE) is a rare central nervous system infection caused by the Balamuthia mandrillaris or Acanthamoeba species. Diagnosis is challenging because of the non-specific clinical presentation, cerebrospinal fluid analysis, and radiological features.
Peng L, Zhou Q, Wu Y, Cao X, Lv Z, Su M, Yu Y, Huang W.   +7 more
europepmc   +5 more sources

An Acute Case of Granulomatous Amoebic Encephalitis-Balamuthia mandrillaris Infection. [PDF]

Intern Med, 2018
A 74-year-old woman who exhibited drowsiness was referred to our hospital. Enhanced head magnetic resonance imaging (MRI) revealed multiple ring-enhancing lesions and lesions showing partial mild hemorrhaging. The patient gradually progressed to a comatose condition with notable brain deterioration of unknown cause on follow-up MRI.
Takei K, Toyoshima M, Nakamura M, Sato M, Shimizu H, Inoue C, Shimizu Y, Yagita K.   +7 more
europepmc   +5 more sources

A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review. [PDF]

BMC Infect Dis, 2023
Abstract Background Balamuthia granulomatous amoebic encephalitis (GAE) is a peculiar parasitic infectious disease of the central nervous system, about 39% of the infected Balamuthia GAE patients were found to be immunocompromised and is extremely rare clinically.
Liu J, Zhang W, Wu S, Zeng T, Luo F, Jiang Q, Yang R.   +6 more
europepmc   +4 more sources

The application of shotgun metagenomics to the diagnosis of granulomatous amoebic encephalitis due to Balamuthia mandrillaris: a case report. [PDF]

BMC Neurol, 2021
Abstract Background Granulomatous amoebic encephalitis (GAE) is an infrequent and fatal infectious disease worldwide. Antemortem diagnosis in this condition is very difficult because clinical manifestations and neuroimaging are nonspecific.
Hirakata S, Sakiyama Y, Yoshimura A, Ikeda M, Takahata K, Tashiro Y, Yoshimura M, Arata H, Yonezawa H, Kirishima M, Higashi M, Hatanaka M, Kanekura T, Yagita K, Matsuura E, Takashima H.   +15 more
europepmc   +5 more sources

Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier. [PDF]

Am J Trop Med Hyg, 2012
A 38-year-old male immunocompetent soldier developed generalized seizures. He underwent surgical debulking and a progressive demyelinating pseudotumor was identified. Serology and molecular testing confirmed a diagnosis of granulomatous amoebic encephalitis caused by Acanthamoeba sp. in this immunocompetent male.
Webster D, Umar I, Kolyvas G, Bilbao J, Guiot MC, Duplisea K, Qvarnstrom Y, Visvesvara GS.   +7 more
europepmc   +4 more sources

Application of ventriculoscopy in granulomatous amoebic encephalitis: a case report in China and literature review. [PDF]

Front Med (Lausanne)
Balamuthia mandrillaris is a kind of brain-eating amoeba leading to granulomatous amoebic encephalitis (GAE) with a high mortality rate and limited effective treatment options. Its underlying pathological mechanisms are still poorly understood. Here, we presented a 58-year-old man with Balamuthia mandrillaris meningoencephalitis, who died 33 days after
Zheng Z, Chen F, Qin L, Lu A, Xu H, Zhao M, Zhao Y.   +6 more
europepmc   +4 more sources

Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. [PDF]

Open Forum Infect Dis, 2015
Abstract Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft.
Salameh A, Bello N, Becker J, Zangeneh T.   +3 more
europepmc   +4 more sources

Genotyping of Acanthamoeba spp. isolated from patients with granulomatous amoebic encephalitis.

Indian J Med Res, 2018
Megha K, Sehgal R, Khurana S.
europepmc   +3 more sources