Results 11 to 20 of about 126,528 (327)

Chronic granulomatous disease [PDF]

open access: bronzeBritish Medical Bulletin, 2016
Chronic granulomatous disease is a clinical condition that stems from inactivating mutations in NOX2 and its auxiliary proteins. Together, these proteins form the phagocyte NADPH oxidase enzyme that generates superoxide. Superoxide (O2ċ-) and its reduced product hydrogen peroxide (H2O2) give rise to several additional reactive oxygen species (ROS ...
Dirk Roos
  +8 more sources

Chronic granulomatous disease [PDF]

open access: bronzeClinical and Experimental Immunology, 2000
A clinical syndrome characterized by recurrent life-threatening Staphylococcus aureus, Proteus or Pseudomonas, hypergammaglobulinaemia, and widespread chronic granulomatous infiltration was first recognized in the paediatric literature between 1954 and 1960 [1–3].
David Goldblatt, Adrian J. Thrasher
openalex   +4 more sources

Vaping-related pulmonary granulomatous disease

open access: yesRespiratory Medicine Case Reports, 2020
The use of electronic cigarettes, or “vaping,” has garnered significant popularity and attention in recent years. Its pulmonary and systemic effects have yet to be fully studied and quantified, and recent reports of vaping-related illnesses and deaths ...
Charlie Lin   +3 more
doaj   +1 more source

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

open access: yes, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi   +58 more
core   +15 more sources

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]

open access: yes, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD   +3 more
core   +1 more source

Chronic granulomatous disease [PDF]

open access: yesThe British Journal of Radiology, 1970
Abstract Chronic granulomatous disease is a hereditable disorder in which polymorphs show diminished capacity for killing bacteria. Defective bactericidal activity results in protracted infection. The lesions of chronic granulomatous disease may affect all systems of the body.
J, Sutcliffe, A R, Chrispin
openaire   +4 more sources

Clinical observation of Сhronic granulomatous disease in a 6-year-old child

open access: yesДетские инфекции (Москва), 2020
Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis.
G. A. Kharchenko, O. G. Kimirilova
doaj   +1 more source

An Unusual Case of Tertiary Syphilis Behaving Like Tongue Squamous Cell Carcinoma. [PDF]

open access: yes, 2018
Syphilis may present with a myriad of oral manifestations in the primary, secondary, and tertiary stages, and may be confused with malignancy. Despite a rise in the incidence of syphilis, tertiary syphilis is exceedingly rare.
Farwell, D Gregory   +2 more
core   +2 more sources

Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]

open access: yes, 2018
AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra   +3 more
core   +2 more sources

Clinic manifestations in granulomatosis with polyangiitis [PDF]

open access: yes, 2016
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco   +7 more
core   +1 more source

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