Results 61 to 70 of about 65,963 (206)

The role of PLAU in polycystic ovary syndrome: activation of STAT3-mediated NLRP3 signaling to promote granulosa cell injury, inflammation, and apoptosis

Applied Biological Chemistry
Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder. Granulosa cell dysfunction is an important factor causing PCOS.PLAU has been shown to be upregulated in granulosa cells of PCOS patients, but its potential ...
Penghua Luo, Canyi Li, Lin Tang, Yongqiang Yang, Long Rao, Xiguang Mao, Lijun Zhong   +6 more
doaj   +1 more source

Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development

Communications Biology, 2021
Tomoko Kawai et al. investigate DNA methylation patterns during granulosa cell differentiation and proliferation. Their results suggest that sequential epigenetic events are essential for progressive changes in granulosa cell differentiation.
Tomoko Kawai, JoAnne S. Richards, Masayuki Shimada   +2 more
doaj   +1 more source

Peripheral and central mechanisms involved in hormonal control of male and female reproduction [PDF]

, 2016
Reproduction involves the integration of hormonal signals acting across multiple systems togenerate a synchronized physiological output. A critical component of reproduction is the luteinizinghormone (LH) surge, which is mediated by estradiol (E2) and ...
Bentley, G. E., Calandra, Ricardo Saul, Micevych, P. E., Paredes, A. H., Rudolph, L. M., Tesone, Marta, Wu, T. J.   +6 more
core   +1 more source

Inductions of granulosa cell luteinization and cumulus expansion are dependent on the fibronectin-integrin pathway during ovulation process in mice. [PDF]

PLoS ONE, 2018
It has been known that EGF-like factor secreted from LH-stimulated granuloma cells acts on granulosa cells and cumulus cells to induce ovulation process.
Hiroya Kitasaka, Tomoko Kawai, S A Masudul Hoque, Takashi Umehara, Youko Fujita, Masayuki Shimada   +5 more
doaj   +1 more source

Downregulating lncRNA NEAT1 induces proliferation and represses apoptosis of ovarian granulosa cells in polycystic ovary syndrome via microRNA-381/IGF1 axis

Journal of Biomedical Science, 2021
Objective Researchers have revealed the combined functions of long noncoding RNAs (lncRNAs) and microRNA (miRNAs) in polycystic ovary syndrome (PCOS). This study aimed to understand the role of nuclear-enriched abundant transcript 1 (NEAT1) and miR-381 ...
Jingran Zhen, Jiangli Li, Xia Li, Xue Wang, Yaling Xiao, Zhengyi Sun, Qi Yu   +6 more
doaj   +1 more source

Multi-scale modeling of follicular ovulation as a reachability problem [PDF]

, 2007
During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called atresia. We have designed a multi-scale mathematical model where ovulation and atresia result from a hormonal controlled ...
Frederique Clément, Michel Sorine, Nki Echenim, Szepessy A., Tomlin C.J.   +4 more
core   +4 more sources

Granulosa cell tumor of testis: Clinicopathological correlation of a rare tumor

Indian Journal of Pathology and Microbiology, 2014
Background: Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors.
Swapnil Ulhas Rane, Santosh Menon, Sangeeta Desai, Ganesh Bakshi, Amit Joshi   +4 more
doaj   +1 more source

OAZ1 knockdown enhances viability and inhibits ER and LHR transcriptions of granulosa cells in geese. [PDF]

PLoS ONE, 2017
An increasing number of studies suggest that ornithine decarboxylase antizyme 1 (OAZ1), which is regarded as a tumor suppressor gene, regulates follicular development, ovulation, and steroidogenesis.
Bo Kang, Dongmei Jiang, Rong Ma, Hui He, Zhixin Yi, Ziyu Chen   +5 more
doaj   +1 more source

Follicle-stimulating hormone is expressed in ovarian follicles of chickens and promotes ovarian granulosa cell proliferation

Journal of Integrative Agriculture, 2021
Follicle-stimulating hormone (FSH), an important hypothalamic-pituitary-gonadal axis (HPG) hormone, is secreted by the pituitary gland. This study confirms that FSH is expressed in chicken follicles at different stages, and positive FSHβ mRNA signals ...
Yu-lin BI, Shu-yan YANG, Hai-yan WANG, Guo-bin CHANG, Guo-hong CHEN   +4 more
doaj   +1 more source

Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]

, 2001
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S., Sinowatz, Fred, Töpfer-Petersen, E.   +2 more
core   +1 more source