Results 41 to 50 of about 4,929,218 (260)

Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor [PDF]

, 2009
Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages.
Friberg, Anders, Larsson, D. G. Joakim,, Billig, Håkan,, Friberg, P. Anders,   +3 more
core   +1 more source

PRMT5 regulates ovarian follicle development by facilitating Wt1 translation

eLife, 2021
Protein arginine methyltransferase 5 (Prmt5) is the major type II enzyme responsible for symmetric dimethylation of arginine. Here, we found that PRMT5 was expressed at high level in ovarian granulosa cells of growing follicles.
Min Chen, Fangfang Dong, Min Chen, Zhiming Shen, Haowei Wu, Changhuo Cen, Xiuhong Cui, Shilai Bao, Fei Gao   +8 more
doaj   +1 more source

Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study [PDF]

, 2011
The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional
Sinowatz, Fred, Rodler, Daniela, Daniela Rodler, Fred Sinowatz, Sasanami, Tomohiro, Tomohiro Sasanami   +5 more
core   +1 more source

Morphological and Hormonal Identification of Porcine Atretic Follicles and Relationship Analysis of Hormone Receptor Levels During Granulosa Cell Apoptosis In vivo

Journal of Integrative Agriculture, 2014
Recent reports have demonstrated that follicular atresia is initiated or caused by granulosa cell apoptosis followed by theca cell degeneration in mammalian ovaries, but the mechanism of follicular atresia is still to be elucidated.
De-bing YU, Min-li YU, Fei LIN, Bao-chun JIANG, Li-na YANG, Si-yu WANG, Ying ZHAO, Zheng-chao WNAG   +7 more
doaj   +1 more source

Transcriptomic analysis of the effects exerted by curcumin on dihydrotestosterone-induced ovarian granulosa cells

Frontiers in Endocrinology
PurposeHyperandrogenism is a leading cause of developmental retardation in ovarian granulosa cells. Previous studies have indicated that curcumin significantly improves follicular dysplasia, a characteristic of the polycystic ovary syndrome.
Dejian Chen, Dejian Chen, Qian Yu, Shuhao Sheng, Lingshi Cai, Jisuo Zheng, Yaling Zhang   +6 more
doaj   +1 more source

Granulosa cell proliferation is inhibited by PGE2 in the primate ovulatory follicle

Animal Cells and Systems, 2020
Prostaglandin E2 (PGE2) is a key paracrine mediator of ovulation. Few specific PGE2-regulated gene products have been identified, so we hypothesized that PGE2 may regulate the expression and/or activity of a network of proteins to promote ovulation.
Patric S. Lundberg, Gil J. Moskowitz, Carmel Bellacose, Esra Demirel, Heidi A. Trau, Diane M. Duffy   +5 more
doaj   +1 more source

Adult granulosa cell tumor

, 2023
ANTECEDENTES: El tumor de células de la granulosa representa del 2 al 5% de las neoplasias del ovario. Su manifestación clínica no siempre es específica.
Sillero Castillo, Ana, Escribano Cobalea, María, López González, Elga   +2 more
core   +1 more source

Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries.

PLoS Genetics, 2018
Women and other mammalian females are born with a finite supply of oocytes that determine their reproductive lifespan. During fetal development, individual oocytes are enclosed by a protective layer of granulosa cells to form primordial follicles that ...
Anqi Fu, Sydney M Oberholtzer, Stefan Bagheri-Fam, Raphael H Rastetter, Claire Holdreith, Valeria L Caceres, Steven V John, Sarah A Shaw, Kathleen J Krentz, Xiaoyun Zhang, Chi-Chung Hui, Dagmar Wilhelm, Joan S Jorgensen   +12 more
doaj   +1 more source

Adult type granulosa cell tumor in adult testis: report of a case and review of the literature

Rare Tumors, 2011
Granulosa cell tumors can be classified into juvenile and adult types and more commonly occur in ovaries. Adult testicular granulosa cell tumors are extremely rare and only 29 cases of adult type have previously been reported.
Zhanyong Bing, Zhao Song, David J. Vaughn   +2 more
doaj   +1 more source

Luteotropic roles of glucocorticoids in rat granulosa cells

Reproductive and Developmental Medicine, 2020
Objective: The study objective was to investigate whether endogenous glucocorticoids directly impact the functions and proliferation/apoptosis of ovarian granulosa cells.
Xin-Yan Huang, Yin-Yan Xu, Juan Xie, Li Wang   +3 more
doaj   +1 more source