Results 51 to 60 of about 4,929,218 (260)

Extraovarian granulosa cell tumor

Indian Journal of Pathology and Microbiology, 2009
Extraovarian granulosa cell tumor (GCT) is a very uncommon tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. One such rare case of extraovarian GCT was encountered in a 58-year-old female who presented with a large intraabdominal lump.
Paul Prabir, Chakraborty Jayati, Chakrabarti Sudipta, Chattopadhyay Bitan   +3 more
openaire   +3 more sources

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

RHOB Regulates Apoptosis of Granulosa Cells in Muscovy Duck Follicles via Mitochondrial Pathway

Animals
Muscovy ducks (Cairina moschata) exhibit strong nesting tendencies, which result in reduced egg-laying performance. The research team previously identified differential expression of the Ras homolog family member B (RHOB) gene in the ovaries of Muscovy ...
Yuexia Liu, Xin Wang, Leyong Li, Yaping Zhang, Senyang Lian, Xu Wu   +5 more
doaj   +1 more source

Expression and alternative splicing of the neural cell adhesion molecule NCAM in human granulosa cells during luteinization [PDF]

, 1994
Freshly aspirated human granulosa cells from pre-ovulatory follicles and granulosa cells luteinized in culture possess the neural cell adhesion molecule (NCAM) of approximate molecular mass of 140,000 and NCAM mRNA as confirmed by S1-nuclease protection ...
Lahr, G., Fro¨hlich, Ulrike, Sterzik, K., Sterzik, Karl, Fröhlich, U., Gratzl, Manfred, Zienecker, R., Lahr, Georgia, Mayerhofer, Artur, Zienecker, Renate   +9 more
core   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

A new isolation and culture method for granulosa cells

, 2021
Granulosa cells are the cell population who have an increasing importance in the female genital system and reproduction. Thus, nowadays in vitro studies to address these cells are also gaining importance and attracts researcher's attention.
Bozdağ, G., Zırh, S., Zirh, Elham Bahador, BOZDAĞ, GÜRKAN, KARAKOÇ SÖKMENSÜER, LALE, Müftüoğlu, S. F., Erol, Suleyman, ZIRH, SELİM, Zırh, E. B., Sökmensuer, L. K., MÜFTÜOĞLU, SEVDA FATMA, Erol, S.   +11 more
core   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

The adipokines progranulin and omentin – novel regulators of basic ovarian cell functions

Reproductive Biology and Endocrinology
The present study aimed to examine the effects of progranulin and omentin on basic ovarian cell functions. For this purpose, we investigated the effects of the addition of progranulin and omentin (0, 0.1, 1, or 10 ng/ml) on the viability, proliferation ...
Alexander V Sirotkin, Zuzana Fabová, Barbora Loncová, Maria Bauerová, Abdel Halim Harrath   +4 more
doaj   +1 more source

Hormonal induction of polo-like kinases (Plks) and impact of Plk2 on cell cycle progression in the rat ovary. [PDF]

PLoS ONE, 2012
The highly conserved polo-like kinases (Plks) are potent regulators of multiple functions in the cell cycle before and during mitotic cell division. We investigated the expression pattern of Plk genes and their potential role(s) in the rat ovary during ...
Feixue Li, Misung Jo, Thomas E Curry, Jing Liu   +3 more
doaj   +1 more source

Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro [PDF]

, 2003
Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured ...
Hunter, M.G., Brankin, V., Mitchell, M.R., Webb, B.   +3 more
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