Results 31 to 40 of about 41,908 (249)
Unicystic Granulosa Cell Tumor [PDF]
Journal of Pathology and Translational Medicine, 2015 Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Nalli R. Sumitra Devi +3 more
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Journal of Ovarian Research, 2017 Background Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the
Wen-Chung Wang +2 more
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The Cultivation of Human Granulosa Cells [PDF]
Acta Medica (Hradec Kralove, Czech Republic), 2008 The major functions of granulosa cells (GCs) include the production of steroids, as well as a myriad of growth factors to interact with the oocyte during its development within the ovarian follicle. Also FSH stimulates GCs to convert androgens (coming from the thecal cells) to estradiol by aromatase.
Lenka Brůčková +7 more
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Reproductive Biology and Endocrinology, 2003 Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured ...
Webb Bob +3 more
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Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study [PDF]
, 2011 The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional
Sinowatz, Fred +5 more
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Granulosa cell proliferation is inhibited by PGE2 in the primate ovulatory follicle
Animal Cells and Systems, 2020 Prostaglandin E2 (PGE2) is a key paracrine mediator of ovulation. Few specific PGE2-regulated gene products have been identified, so we hypothesized that PGE2 may regulate the expression and/or activity of a network of proteins to promote ovulation.
Patric S. Lundberg +5 more
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PRMT5 regulates ovarian follicle development by facilitating Wt1 translation
eLife, 2021 Protein arginine methyltransferase 5 (Prmt5) is the major type II enzyme responsible for symmetric dimethylation of arginine. Here, we found that PRMT5 was expressed at high level in ovarian granulosa cells of growing follicles.
Min Chen +8 more
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Expression and alternative splicing of the neural cell adhesion molecule NCAM in human granulosa cells during luteinization [PDF]
, 1994 Freshly aspirated human granulosa cells from pre-ovulatory follicles and granulosa cells luteinized in culture possess the neural cell adhesion molecule (NCAM) of approximate molecular mass of 140,000 and NCAM mRNA as confirmed by S1-nuclease protection ...
Lahr, G. +9 more
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A new isolation and culture method for granulosa cells
, 2021 Granulosa cells are the cell population who have an increasing importance in the female genital system and reproduction. Thus, nowadays in vitro studies to address these cells are also gaining importance and attracts researcher's attention.
Bozdağ, G. +11 more
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Frontiers in EndocrinologyPurposeHyperandrogenism is a leading cause of developmental retardation in ovarian granulosa cells. Previous studies have indicated that curcumin significantly improves follicular dysplasia, a characteristic of the polycystic ovary syndrome.
Dejian Chen +6 more
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