Results 11 to 20 of about 35,653 (216)
Oocyte-granulosa cell interactions [PDF]
Human Reproduction Update, 2000 In the past, different protocols of ovulation induction, aimed to overcome problems of anovulatory infertility in humans, have been developed during IVF programmes. However, administration of exogenous hormones may cause severe health problems, e.g. ovarian hyperstimulation syndrome.
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Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman: A Case Report and Literature Review [PDF]
Journal of Pathology and Translational Medicine, 2018 Gynandroblastoma is an extremely rare sex cord-stromal tumor with both female (granulosa cell tumor) and male (Sertoli-Leydig cell tumor) elements. Juvenile granulosa cell tumors are also very rare and are so named because they usually occur in children ...
Nu Ri Jang +5 more
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Journal of Ovarian Research, 2017 Background Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the
Wen-Chung Wang +2 more
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Unicystic Granulosa Cell Tumor [PDF]
Journal of Pathology and Translational Medicine, 2015 Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Nalli R. Sumitra Devi +3 more
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The Cultivation of Human Granulosa Cells [PDF]
Acta Medica (Hradec Kralove, Czech Republic), 2008 The major functions of granulosa cells (GCs) include the production of steroids, as well as a myriad of growth factors to interact with the oocyte during its development within the ovarian follicle. Also FSH stimulates GCs to convert androgens (coming from the thecal cells) to estradiol by aromatase.
Lenka Brůčková +7 more
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Reproductive Biology and Endocrinology, 2003 Oocyte control of granulosa and theca cell function may be mediated by several growth factors via a local feedback loop(s) between these cell types. This study examined both the role of oocyte-secreted factors on granulosa and thecal cells, cultured ...
Webb Bob +3 more
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Granulosa cell proliferation is inhibited by PGE2 in the primate ovulatory follicle
Animal Cells and Systems, 2020 Prostaglandin E2 (PGE2) is a key paracrine mediator of ovulation. Few specific PGE2-regulated gene products have been identified, so we hypothesized that PGE2 may regulate the expression and/or activity of a network of proteins to promote ovulation.
Patric S. Lundberg +5 more
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PRMT5 regulates ovarian follicle development by facilitating Wt1 translation
eLife, 2021 Protein arginine methyltransferase 5 (Prmt5) is the major type II enzyme responsible for symmetric dimethylation of arginine. Here, we found that PRMT5 was expressed at high level in ovarian granulosa cells of growing follicles.
Min Chen +8 more
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Frontiers in EndocrinologyPurposeHyperandrogenism is a leading cause of developmental retardation in ovarian granulosa cells. Previous studies have indicated that curcumin significantly improves follicular dysplasia, a characteristic of the polycystic ovary syndrome.
Dejian Chen +6 more
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Journal of Integrative Agriculture, 2014 Recent reports have demonstrated that follicular atresia is initiated or caused by granulosa cell apoptosis followed by theca cell degeneration in mammalian ovaries, but the mechanism of follicular atresia is still to be elucidated.
De-bing YU +7 more
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