Results 51 to 60 of about 4,453,459 (256)
Granulosa cell apoptosis: Transcriptional regulation by the nuclear progesterone receptor [PDF]
, 2009 Ovarian follicle atresia caused by granulosa cell apoptosis is a central process in normal female physiology. Progesterone has been reported to be a survival factor in granulosa cells at several developmental stages.
Friberg, Anders +3 more
core +1 more source
Journal of Ovarian Research, 2020 Background We elucidated the role of specific MicroRNAs (miRNAs) in the development of polycystic ovary syndrome (PCOS) and explained the changes in the proliferation of granulosa cells. Excised ovarian cortex specimens were collected for miRNA profiling
Zhengfang Xiong +6 more
doaj +1 more source
The effect of total flavonoids of Epimedium on granulosa cell development in laying hens
Poultry Science, 2020 To investigate the impact of total flavonoids of Epimedium (TFE) on the development of follicles of laying hens, 3 types of follicles including primary, prehierarchical, and preovulatory follicles were selected to obtain the follicular granulosa cells ...
Yu Guo +7 more
doaj +1 more source
Proprotein convertase furin regulates apoptosis and proliferation of granulosa cells in the rat ovary. [PDF]
PLoS ONE, 2013 Folliculogenesis is tightly controlled by a series of hormones, growth factors and cytokines, many of which are secreted as proproteins and require processing by proteases before becoming functional.
Xiaokui Yang +8 more
doaj +1 more source
Journal of Integrative Agriculture, 2021 Follicle-stimulating hormone (FSH), an important hypothalamic-pituitary-gonadal axis (HPG) hormone, is secreted by the pituitary gland. This study confirms that FSH is expressed in chicken follicles at different stages, and positive FSHβ mRNA signals ...
Yu-lin BI +4 more
doaj +1 more source
Advanced Science, EarlyView.A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells [PDF]
, 2006 The most common fate of developing ovarian follicles is demise due to a process known as atresia. Regulation of atresia is dependent on the developmental stage of the follicles, resulting in a continuous reduction of the number of follicles as they ...
Rung, Emilia
core +1 more source
The adipokines progranulin and omentin – novel regulators of basic ovarian cell functions
Reproductive Biology and EndocrinologyThe present study aimed to examine the effects of progranulin and omentin on basic ovarian cell functions. For this purpose, we investigated the effects of the addition of progranulin and omentin (0, 0.1, 1, or 10 ng/ml) on the viability, proliferation ...
Alexander V Sirotkin +4 more
doaj +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source