Results 31 to 40 of about 36,983 (206)
Oocyte-granulosa cell interactions [PDF]
Human Reproduction Update, 2000 In the past, different protocols of ovulation induction, aimed to overcome problems of anovulatory infertility in humans, have been developed during IVF programmes. However, administration of exogenous hormones may cause severe health problems, e.g. ovarian hyperstimulation syndrome.
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TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways. [PDF]
PLoS ONE, 2015 Connective tissue growth factor (CTGF), which is also called CCN2, is a secreted matricellular protein. CTGF regulates various important cellular functions by interacting with multiple molecules in the microenvironment.
Jung-Chien Cheng +4 more
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Frontiers in Endocrinology, 2022 The mechanisms underlining pathogenesis of polycystic ovary syndrome (PCOS) remain largely unknown. Dysfunction of ovarian granulosa cells plays an important role.
Yan Deng +14 more
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Unicystic Granulosa Cell Tumor [PDF]
Journal of Pathology and Translational Medicine, 2015 Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Nalli R. Sumitra Devi +3 more
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The Cultivation of Human Granulosa Cells [PDF]
Acta Medica (Hradec Kralove, Czech Republic), 2008 The major functions of granulosa cells (GCs) include the production of steroids, as well as a myriad of growth factors to interact with the oocyte during its development within the ovarian follicle. Also FSH stimulates GCs to convert androgens (coming from the thecal cells) to estradiol by aromatase.
Lenka Brůčková +7 more
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Movento influences development of granulosa cells and ovarian follicles and FoxO1 and Vnn1 gene expression in BALB/c mice [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Pesticides has wide range of infertility in female reproductive. This study was done to evaluate the effect of movento pesticide on development of granulosa cells and ovarian follicles and FoxO1 and Vnn1 gene expression in BALB/c mice ...
Sakineh Kaboli Kafshgiri +4 more
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Granulosa cell tumor of the ovary
Cancer Treatment Reviews, 2008 Ovarian granulosa cell tumors (GCTs) are uncommon neoplasms that arise from the sex-cord stromal cells of the ovary. GCTs are characterized by long natural history and their tendency to recur years after the initial diagnosis. They present with symptoms and signs due to estradiol secretion, including vaginal bleeding and precocious puberty ...
Pectasides, D. +2 more
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Frontiers in Cell and Developmental BiologyThe endocrine functions exerted by ovarian granulosa cells (GCs) are crucial factors in maintaining follicle development, as oocyte development relies on providing energy substrates and cytokines by ovarian granulosa cells.
Shan Han +7 more
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GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. [PDF]
PLoS Genetics, 2017 Folliculogenesis is a progressive and highly regulated process, which is essential to provide ova for later reproductive life, requires the bidirectional communication between the oocyte and granulosa cells.
Chen Jiang +12 more
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Granulosa Cells: Central Regulators of Female Fertility
EndocrinesBackground: Granulosa cells are somatic cells within the ovarian follicle. As the primary site of estradiol production, they are critical regulators of several aspects of female reproduction.
Luis Fernando Schütz +1 more
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