Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
, 1993 Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J. +5 more
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Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy
Frontiers in Cell and Developmental Biology, 2022 Aquaporin-8 (AQP8), a member of the aquaporin family, is strongly expressed in follicular granulosa cells, which could affect the hormone secretion level in females.
Binbin Huang +9 more
doaj +1 more source
ERK1/2-SOX9/FOXL2 axis regulates ovarian steroidogenesis and favors the follicular–luteal transition
Life Science Alliance, 2023 ERK1/2 negatively regulates estradiol synthesis while positively regulating progesterone production in ovarian granulosa cells via the ERK1/2-SOX9/FOXL2 axis. Estradiol and progesterone are the primary sex steroids produced by the ovary. Upon luteinizing
Vijay Simha Baddela +4 more
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The Cultivation of Human Granulosa Cells [PDF]
Acta Medica (Hradec Kralove, Czech Republic), 2008 The major functions of granulosa cells (GCs) include the production of steroids, as well as a myriad of growth factors to interact with the oocyte during its development within the ovarian follicle. Also FSH stimulates GCs to convert androgens (coming from the thecal cells) to estradiol by aromatase.
Lenka Brůčková +7 more
openaire +3 more sources
Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]
, 2014 Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya +4 more
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Induction of Ski Protein Expression upon Luteinization in Rat Granulosa Cells [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 Ski protein is implicated in proliferation/differentiation in a variety of cells. We had previously reported that Ski protein is present in granulosa cells of atretic follicles, but not in preovulatory follicles, suggesting that Ski has a role in ...
Hyun Kim +7 more
doaj +1 more source
, 2009 For decades, scientists have thought that female mammals are born with a lifetime supply of oocytes in the ovary, irreversibly destined to decline after birth.
Tomaszczuk-Kossowska, Katarzyna
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Oocyte-granulosa cell interactions [PDF]
Human Reproduction Update, 2000 In the past, different protocols of ovulation induction, aimed to overcome problems of anovulatory infertility in humans, have been developed during IVF programmes. However, administration of exogenous hormones may cause severe health problems, e.g. ovarian hyperstimulation syndrome.
openaire +2 more sources
Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]
, 1991 In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Lahr, G. +2 more
core +1 more source
Insulin signalling in granulosa cells [PDF]
, 2012 Polycystic ovary syndrome (PCOS) is characterised by hyperandrogenism and insulin resistance. Granulosa cells in PCOS demonstrate impaired insulin-induced glucose uptake and lactate accumulation, suggesting a post receptor, signalling pathway-specific
Joharatnam, Jalini
core +2 more sources