Isolation of Human Cumulus Granulosa Cells
Van Tıp Dergisi, 2022 INTRODUCTION: Follicles are the basic functional units of the ovary. It is characterized by the growth and development of ovarian follicles, proliferation and differentiation of granulosa cells.
Murat Serkant Ünal, Cihan Kabukçu
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BCAS2 regulates granulosa cell survival by participating in mRNA alternative splicing
Journal of Ovarian Research, 2023 Background Granulosa cell proliferation and differentiation are essential for follicle development. Breast cancer amplified sequence 2 (BCAS2) is necessary for spermatogenesis, oocyte development, and maintaining the genome integrity of early embryos in ...
Xiaohong Yao +11 more
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SUMOylation of mouse p53b by SUMO-1 promotes its pro-apoptotic function in ovarian granulosa cells. [PDF]
PLoS ONE, 2013 Follicular atresia is a process of spontaneous degradation of follicles, hindering growth and development in the mammalian ovary. Previous studies showed that follicular atresia was caused by apoptosis of granulosa cells, for which a number of apoptosis ...
Xiao-Ming Liu +4 more
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Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress. [PDF]
PLoS ONE, 2017 Various environmental insults including diseases, heat and oxidative stress could lead to abnormal growth, functions and apoptosis in granulosa cells during ovarian follicle growth and oocyte maturation.
Mohammed Saeed-Zidane +8 more
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eLife, 2023 An in vitro model of human ovarian follicles would greatly benefit the study of female reproduction. Ovarian development requires the combination of germ cells and several types of somatic cells.
Merrick D Pierson Smela +13 more
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Effect of Vitamin D3 on Mitochondrial Biogenesis in Granulosa Cells Derived from Polycystic Ovary Syndrome [PDF]
International Journal of Fertility and Sterility, 2020 Background Polycystic ovary syndrome (PCOS) is an endocrine disorder diagnosed by anovulation hyperandro- genism. Hyperandrogenism increases apoptosis, which will eventually disturb follicular growth in PCOS patients.
Zahra Safaei +6 more
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Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]
, 1992 We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J. +3 more
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Effects of angiogenin on granulosa and theca cell function in cattle
Animal, 2017 Angiogenin is a member of the ribonuclease A superfamily of proteins that has been implicated in stimulating angiogenesis but whether angiogenin can directly affect ovarian granulosa or theca cell function is unknown.
J.L. Dentis +3 more
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Unicystic Granulosa Cell Tumor [PDF]
Journal of Pathology and Translational Medicine, 2015 Granulosa cell tumors are the most frequent sex cord stromal tumor and account for approximately 5% of all primary ovarian tumors. About 5% occur before puberty and 40% occur in the menopausal age group; however, these tumors have an indolent biological behavior [1].
Nalli R. Sumitra Devi +3 more
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Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells [PDF]
, 1993 Oxytocin and its receptor are found in the corpus luteum in a variety of species, including the human. In the present study we used fura-2 microfluorimetry to investigate whether activation of the oxytocin receptor of cultured human granulosa-lutein ...
Wiemann, M. +4 more
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