Results 101 to 110 of about 829,286 (307)

Graph4Med: a web application and a graph database for visualizing and analyzing medical databases. [PDF]

open access: yesBMC Bioinformatics, 2022
Schäfer J   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Fragment Merging Using a Graph Database Samples Different Catalogue Space than Similarity Search. [PDF]

open access: yesJ Chem Inf Model, 2023
Wills S   +8 more
europepmc   +1 more source

Survey: Graph Databases

open access: yes
Graph databases have become essential tools for managing complex and interconnected data, which is common in areas like social networks, bioinformatics, and recommendation systems. Unlike traditional relational databases, graph databases offer a more natural way to model and query intricate relationships, making them particularly effective for ...
Coimbra, Miguel E.   +3 more
openaire   +2 more sources

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

Graph-Based Automation of Threat Analysis and Risk Assessment for Automotive Security

open access: yesInformation
The proliferation of cyber–physical systems in modern vehicles, characterized by densely interconnected Electronic Control Units (ECUs) and heterogeneous communication networks, has significantly expanded the automotive attack surface. Traditional Threat
Mera Nizam-Edden Saulaiman   +2 more
doaj   +1 more source

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