Results 101 to 110 of about 201,580 (310)
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
We present a graphical calculus, which allows mathematical formulae to be represented and reasoned about using a visual representation. We define how a formula may be represented by a graph, and present a number of laws for transforming graphs, and describe the effects these transformations have on the corresponding formulae.
Curtis, S, Lowe, G
openaire +2 more sources
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Великая Отечественная война в современном искусстве Сибири
Статья посвящена экспозиции выставки «Война и мир в творчестве современных художников России», организованной Региональным отделением Урала, Сибири и Дальнего Востока Российской академии художеств к 80-летию Победы.
Белокурова, С.М. +1 more
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Accelerating the Adaptive Tempering Monte Carlo Method with CUDA Graphics Processing Units
Clifford T. Hall
openalex +1 more source
Evaluation of use of Graphics Interchange Format (GIF) animations in mathematics education [PDF]
Altıntaş Esra +2 more
openalex +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source

