Results 41 to 50 of about 4,323 (176)
Graves’ disease and exophthalmos — a mask for meningioma
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Kamila Mitka +3 more
doaj +1 more source
Current concepts regarding Graves’ orbitopathy
AbstractGraves’ orbitopathy (GO) is an orbital autoimmune disorder and the main extrathyroidal manifestation of Graves’ disease, the most common cause of hyperthyroidism. GO affects about 30% of Graves’ patients, although fewer than 10% have severe forms requiring immunosuppressive treatments.
Luigi Bartalena, Maria Laura Tanda
openaire +2 more sources
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
Graves’ orbitopathy is an inflammatory disorder that causes changes in different structures close to the eye. Accurate and consistent diagnoses are essential to improve the quality of life for Graves’ orbitopathy patients.
Sanghyuck Lee +3 more
doaj +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
Graves’ orbitopathy: lessons from Representational Art
Graves’ orbitopathy (GO) is an autoimmune orbital disorder which occurs most commonly in patients with Graves’ disease, less frequently in patients with chronic autoimmune thyroiditis.
Francesco Trimarchi +3 more
doaj +1 more source
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
Background Treatment of moderate to severe Graves’ orbitopathy (GO) is based mainly on intravenous pulses of methylprednisolone. High doses of methylprednisolone can exert several adverse effects, some of which might be life-threatening. The objective of
Dorota Walasik-Szemplińska +2 more
doaj +1 more source
Purpose Thyroid eye disease (TED) is the most common orbital disorder in adults. Its initial clinical manifestations are heterogeneous and may influence early diagnosis and management. However, limited data exist on real‐world perspectives from oculoplastic surgeons who frequently manage patients with TED.
Shiqi Hui +4 more
wiley +1 more source
Thyroid associated orbitopathy
Thyroid associated orbitopathy, also known as Graves′ orbitopathy, is typically a self-limiting autoimmune process associated with dysthyroid states.
Rajat Maheshwari, Ezekiel Weis
doaj +1 more source

