Results 11 to 20 of about 6,270 (167)
Autophagy in graves’ ophthalmopathy [PDF]
Graves’ ophthalmopathy (GO) is an inflammatory autoimmune disease that affects the eyes. It can significantly alter the quality of life in patients because of its distinctive pathological appearance and the effect on vision.
Yu-Qing Chen +6 more
doaj +2 more sources
Graves’ ophthalmopathy – thyroid eye disease
Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka +3 more
doaj +5 more sources
Postural variation of exophthalmometry in Graves′ ophthalmopathy
30 patients with Graves′ ophthalmopathy were subjected to exophthalmometry in the upright and supine positions to determine if the difference in exophthalmometer readings in these two situations are significantly different and would help in ...
Asad Rajvardhan +3 more
doaj +1 more source
Clinical evaluation of Graves ophthalmopathy [PDF]
Introduction. Graves ophthalmopathy is an autoimmune disease, which is the consequence of thyroid dysfunction. Ocular manifestations occur in 50% of patients with Graves disease.
Janićijević-Petrović Mirjana A. +5 more
doaj +2 more sources
Treatment of Graves' ophthalmopathy
Graves' ophthalmopathy is one of most frequent extrathyroid manifestation of autoimmune thyroid diseases. In 3–5% cases it has severe progress and requires specific therapy.
doaj +2 more sources
The relationship between Graves’ ophthalmopathy and dry eye syndrome
Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves&rsquo ...
Selter JH, Gire AI, Sikder S
doaj +1 more source
Update on the medical treatment of Graves’ ophthalmopathy
Gregory J Griepentrog, James A GarrityDepartment of Ophthalmology, Mayo Clinic, Rochester, MN, USAPurpose: To review recent advances in the understanding of Graves’ ophthalmopathy (GO) pathogenesis as well as discuss current and future medical ...
Gregory J Griepentrog, James A Garrity
doaj +1 more source
Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy. [PDF]
Objective The understanding regarding the role of orbital magnetic resonance imaging (MRI) in predicting the prognosis of radioactive iodine‐131 (I‐131) therapy for patients with inactive Graves’ ophthalmopathy (GO) is limited. Therefore, this study aimed to explore the application of MRI quantitative measurements of orbital structures in radioactive I‐
Wang M, Shen ZY, Wu XW.
europepmc +2 more sources
TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition. [PDF]
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Zhang Y +16 more
europepmc +2 more sources
Age Influences the Severity of Graves' Ophthalmopathy
This study compared the ocular manifestations of Graves' disease in different age groups and between genders. This was a retrospective study with a chart review of 210 patients seen in the Kaohsiung Veterans General Hospital Ophthalmology Department from
Muh-Chiou Lin +3 more
doaj +2 more sources

