Results 31 to 40 of about 5,054 (133)

Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]

, 2017
BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Antonelli, A, Couch, SM, Dailey, RA, Douglas, RS, Ezra, DG, Fleming, JC, Gabriel, K, Gigantelli, JW, Goldberg, RA, Harris, GJ, Hayek, BR, Hink, EM, Kahaly, GJ, Magni, G, Salvi, M, Shriver, EM, Smith, TJ, Tang, RA, Woodward, RM   +18 more
core   +1 more source

Rare concurrent ocular myasthenia gravis and Graves’ ophthalmopathy in a man with Poland syndrome: a case report

BMC Neurology, 2020
Background Ocular myasthenia gravis and Graves’ ophthalmopathy are autoimmune diseases that are mediated by membrane receptors and share many identical clinical processes.
Jingqun Tang, Chao Qin
doaj   +1 more source

Clinical and Radiological Findings in Patients with Newly Diagnosed Graves’ Ophthalmopathy

International Journal of Endocrinology, 2021
Background. Graves’ ophthalmopathy is the most common extrathyroidal manifestation of Graves’ disease. The objective of this study was to investigate the clinical ophthalmological and MRI findings in newly diagnosed Graves’ ophthalmopathy. Methods.
Yakup Cevik, Hande Taylan Sekeroglu, Burce Ozgen, Kadriye Erkan Turan, Ali Sefik Sanac   +4 more
doaj   +1 more source

Oftalmopatía tiroidea: determinación de parámetros de actividad clínica de la oftalmopatía tiroidea como factor pronóstico de respuesta al tratamiento inmunosupresor [PDF]

, 2005
Objective: To determine the usefulness of the clinical, biochemical and thyroid imaging parameters in patients with thyroid-associated ophthalmopathy, in predicting their response to immunosuppressive treatment.
Belzunce, A. (Arnaldo), Casellas, M. (M.), Garcia-Gomez, P.J. (Pío J.), Heras-Mulero, H. (Henar), Moreno-Montañes, J. (Javier)   +4 more
core   +1 more source

Modified Deep Lateral Wall Decompression Surgery in the Treatment of Thyroid‐Associated Ophthalmopathy: A Retrospective Evaluation

Eye &ENT Research, Volume 3, Issue 1, Page 5-10, March 2026.
ABSTRACT Background Thyroid‐associated ophthalmopathy (TAO) may lead to severe exophthalmos and dysthyroid optic neuropathy (DON), which can threaten visual function. Orbital decompression surgery is often required when medical therapy is insufficient; however, traditional deep lateral wall decompression techniques remain associated with several ...
Shuo Wu, Jiahong Lao, Rongrong Ge, Zhaohui Shi, Qintai Yang   +4 more
wiley   +1 more source

The psychosocial and clinical outcomes following orbital decompression surgery for thyroid eye disease and predictors of change in quality of life [PDF]

, 2015
Objective: Thyroid eye disease (TED) has been found to reduce quality of life for many patients due to changes in their appearance and vision, although some appear to adjust better than others. This study was designed to investigate whether a patient’s
Ezra, D. G., Hirani, S. P., McBain, H. B., Newman, S. P., Rose, G. E., Wickwar, S.   +5 more
core   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

“Influence of Clinically Active Graves’ Ophthalmopathy on Spherical Equivalent and Visual Acuity”

Clinical Ophthalmology, 2022
Jasenka Petrovic Jurcevic,1 Marko Jurcevic,2 Mateja Jagic,3 Anamarija Jazbec,4 Kresimir Mandic,5 Jelena Juri Mandic5 1Medical School University of Zagreb, PhD Candidate on the Programme “Biomedicine and Health”, Zagreb, Croatia; 2University of Zagreb ...
Petrovic Jurcevic J, Jurcevic M, Jagic M, Jazbec A, Mandic K, Juri Mandic J   +5 more
doaj  

The Diagnostic Value of Mean Apparent Propagator‐MRI in Dysthyroid Optic Neuropathy: A Quantitative Analysis of the Entire Visual Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The diagnostic model combining orbital and intracranial MAP‐MRI parameters could significantly optimize diagnostic efficiency of dysthyroid optic neuropathy. Comprehensive MAP‐MRI parameters analysis of the entire visual pathway enables a deeper understanding of disease involvement, provides novel insights into the early accurate diagnosis and ...
Mengsha Zou, Dide Wu, Yanglei Cheng, Haodong Qin, Zhiyun Yang, Shubin Hong, Hongzhang Zhu, Cui Yan   +7 more
wiley   +1 more source

Endoscopic orbital decompression for Graves' ophthalmopathy [PDF]

, 2002
Graves’ disease may occasionally result in significant proptosis that is either cosmetically unacceptable or causes visual loss. This has traditionally been managed surgically by external decompression of the orbital bony skeleton. Trans-nasal endoscopic
Carney, A., Thorpe, M., Wee, D., Wormald, P.   +3 more
core   +1 more source