Results 11 to 20 of about 268,622 (261)

Computer aided volumetric assessment of orbital structures in patients with Graves' orbitopathy: correlation with serum thyroid antiperoxidase antibodies and disease activity [PDF]

International ophtalmology, 2023
Introduction: Graves' disease is an autoimmune disorder. Goiter and Graves' orbitopathy are frequently seen clinically. It would be helpful for the diagnosis, grading, prognosis, and treatment of this condition if it was possible to find serum biomarkers
Abalo Lojo, Jose M., Bande, Manuel F, González García, Francisco, Paniagua Fernández, Laura   +3 more
core   +2 more sources

Significance of HLA in Graves’ disease and Graves’ orbitopathy in Asian and Caucasian populations – a systematic review

Frontiers in Immunology, 2023
IntroductionGraves’ disease (GD) and Graves’ orbitopathy (GO) development were suspected to be HLA-related in both Asian and Caucasian populations. However, most studies were performed with application of serological methods or low resolution genetic ...
Magdalena Stasiak, Bartłomiej Stasiak, Katarzyna Zawadzka-Starczewska, Andrzej Lewiński, Andrzej Lewiński   +4 more
doaj   +2 more sources

Update on the surgical management of Graves' orbitopathy. [PDF]

Front Endocrinol (Lausanne), 2022
Graves’ orbitopathy (GO) is a complex autoimmune disorder of the orbit that causes the eye to appear disfigured. GO is typically associated with Graves’ disease, an inflammatory autoimmune condition that is caused by thyrotropin receptor autoantibodies ...
Baeg J, Choi HS, Kim C, Kim H, Jang SY.
europepmc   +2 more sources

THE 2021 EUROPEAN GROUP ON GRAVES' ORBITOPATHY (EUGOGO) CLINICAL PRACTICE GUIDELINES FOR THE MEDICAL MANAGEMENT OF GRAVES' ORBITOPATHY.

European Journal of Endocrinology, 2021
Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease (GD). Choice of treatment should be based on assessment of clinical activity and severity of GO.
L. Bartalena, G. Kahaly, L. Baldeschi, C. Dayan, A. Eckstein, C. Marcocci, M. Marinò, B. Vaidya, W. Wiersinga   +8 more
semanticscholar   +1 more source

Significance of HLA in the development of Graves' orbitopathy. [PDF]

Genes Immun, 2023
Graves’ disease (GD), similarly to most autoimmune disease, is triggered by environmental factors in genetically predisposed individuals. Particular HLA alleles increase or decrease GD risk.
Stasiak M, Zawadzka-Starczewska K, Tymoniuk B, Stasiak B, Lewiński A.   +4 more
europepmc   +2 more sources

Strabismus surgery in topical anaesthesia with intraoperative suture adjustment in Graves' orbitopathy. [PDF]

Acta Ophthalmol
Abstract Purpose To report the results of strabismus surgery in a series of patients with Graves' orbitopathy (GO), using topical anaesthesia with intraoperative suture adjustment. Methods All first‐time strabismus surgeries in patients with GO in our department during the years 2014–2021 (n = 45) were assessed retrospectively.
Haugen OH, Mellgren AEC, Norli M, Ueland HO.   +3 more
europepmc   +2 more sources

Gut Microbiome Associated With Graves Disease and Graves Orbitopathy: The INDIGO Multicenter European Study

Journal of Clinical Endocrinology and Metabolism, 2023
Context Gut bacteria can influence host immune responses but little is known about their role in tolerance-loss mechanisms in Graves disease (GD; hyperthyroidism caused by autoantibodies, TRAb, to the thyrotropin receptor, TSHR) and its progression to ...
F. Biscarini, G. Masetti, I. Muller, H. Verhasselt, D. Covelli, G. Colucci, Lei Zhang, M. Draman, O. Okosieme, P. Taylor, C. Daumerie, M. Burlacu, M. Marinò, D. Ezra, P. Perros, S. Plummer, A. Eckstein, M. Salvi, J. Marchesi, M. Ludgate   +19 more
semanticscholar   +1 more source

A review of TSHR- and IGF-1R-related pathogenesis and treatment of Graves’ orbitopathy

Frontiers in Immunology, 2023
Graves’ orbitopathy (GO) is an organ-specific autoimmune disease, but its pathogenesis remains unclear. There are few review articles on GO research from the perspective of target cells and target antigens.
Xuejiao Cui, Futao Wang, Cong Liu
semanticscholar   +1 more source

Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced disease [PDF]

Microbiome, 2021
Graves’ disease (GD) is an autoimmune condition in which autoantibodies to the thyrotropin receptor (TSHR) cause hyperthyroidism. About 50% of GD patients also have Graves’ orbitopathy (GO), an intractable disease in which expansion of the orbital ...
Sajad Moshkelgosha, Hedda Luise Verhasselt, Giulia Masetti, Danila Covelli, Filippo Biscarini, Mareike Horstmann, Anke Daser, Astrid M. Westendorf, Christoph Jesenek, Svenja Philipp, Salvador J. Díaz‐Cano, J. Paul Banga, Daryn R. Michael, Sue Plummer, Julian R. Marchesi, Anja Eckstein, Marian Ludgate, Utta Berchner‐Pfannschmidt   +17 more
openalex   +2 more sources

Presentation of Graves' orbitopathy within European Group On Graves' Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III). [PDF]

Br J Ophthalmol, 2023
Background Graves’ orbitopathy (GO) is subject to epidemiological and care-related changes. Aim of the survey was to identify trends in presentation of GO to the European Group On Graves’ Orbitopathy (EUGOGO) tertiary referral centres and initial ...
Schuh A, Ayvaz G, Baldeschi L, Baretić M, Bechtold D, Boschi A, Brix TH, Burlacu MC, Ciric J, Covelli D, Currò N, Donati S, Eckstein AK, Fichter N, Führer D, Horn M, Jabłońska-Pawlak A, Juri Mandić J, Kahaly GJ, Konuk O, Langbein A, Lanzolla G, Marcocci C, Marinò M, Miśkiewicz P, Beleslin BN, Pérez-Lázaro A, Pérez-López M, Ponto KA, Quinn A, Rudofsky G, Salvi M, Schittkowski MP, Tanda ML, Toruner F, Vaidya B, Hintschich CR.   +36 more
europepmc   +2 more sources