Results 31 to 40 of about 7,511 (159)

Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future. [PDF]

open access: yes, 2018
Thyroid-associated orbitopathy (TAO) is the most common autoimmune disease of the orbit. It occurs more often in patients presenting with hyperthyroidism, characteristic of Graves' disease, but may be associated with hypothyroidism or euthyroidism.
De Los Angeles Gracia, M.   +4 more
core   +3 more sources

Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management [PDF]

open access: yes, 2017
INTRODUCTION: Dysthyroid optic neuropathy (DON) is a severe manifestation of thyroid eye disease (TED) that can result in permanent vision loss. Management is complex, multidisciplinary, and involves medical and/or surgical therapies.
Blandford, Alexander D.   +3 more
core   +1 more source

Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]

open access: yes, 2017
BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Antonelli, A   +18 more
core   +1 more source

Isolated primary amyloidosis of the inferior rectus muscle mimicking Graves’ orbitopathy

open access: yesEinstein (São Paulo)
The diagnosis of Graves’ orbitopathy is usually straightforward. However, orbital diseases that mimick some clinical signs of Graves’ orbitopathy may cause diagnostic confusion, particularly when associated to some form of thyroid dysfunction.
Mário Luiz Ribeiro Monteiro   +2 more
doaj   +1 more source

Graves' orbitopathy treated with immunosuppressive therapy and orbital radiotherapy in a tertiary care endocrine centre: case series

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016
Graves’ Orbitopathy (GO) is a localized entity of Graves’ disease, which is a challenging disease to treat. We describe 6 cases of moderate to severe GO who presented to our endocrine centre, with a mean age of 48.6 years and equal gender distribution ...
D. C. Kottahachchi   +4 more
doaj   +1 more source

Endoscopic orbital decompression for Graves′ orbitopathy

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Aim: To study the efficacy of endonasal endoscopic orbital decompression in cases of Graves′ orbitopathy. Material and Methods: A total of 24 orbits in 12 patients underwent endoscopic orbital decompression for graves orbitopathy in the period between ...
Priti Lal, Alok Thakar, Nikhil Tandon
doaj   +1 more source

Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei   +10 more
wiley   +1 more source

The Value of Multidetector Computed Tomography of Orbits in Globe Protrusion in Comparison to Hertel Exophthalmometry

open access: yesActa Clinica Croatica, 2017
The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. Th e aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel ...
Igor Đorić   +7 more
doaj   +1 more source

Graves' ophthalmopathy [PDF]

open access: yes, 2009
A 40-year-old woman who recently received a diagnosis of Graves' disease comes for a follow-up visit. She has been taking methimazole, at a dose of 10 mg daily, and is now euthyroid, but for the past 3 months, she has had bothersome eye symptoms ...
Bartalena, Luigi   +1 more
core   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu   +12 more
wiley   +1 more source

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