Results 161 to 170 of about 9,117 (217)

Assessment of Schlemm's canal with swept-source optical coherence tomography in Graves' ophthalmopathy. [PDF]

open access: yesGraefes Arch Clin Exp Ophthalmol
Gün RD   +3 more
europepmc   +1 more source

Graves' Ophthalmopathy [PDF]

open access: yesNew England Journal of Medicine, 2010
Graves' orbitopathy is part of an autoimmune systemic disease which compiles hyperthyroidism, orbitopathy, dermopathy and acropachy. Stimulating antibodies against the TSH receptor play the central pathogenetic role. Main symptoms of Graves' orbitopathy comprise soft tissue inflammation, proptosis impairment of ocular motility and lid retraction ...
A, Eckstein, J, Esser
exaly   +7 more sources

Treatment of Graves’ ophthalmopathy

Medicina Clínica (English Edition), 2021
Graves' ophthalmopathy is an inflammatory disease with primary involvement of the extraocular muscles and the orbit. It encompasses the most common extra-thyroid manifestation in patients with Graves-Basedow disease. The underlying cause is molecular mimicry with the TSH receptor in ocular fibroblasts, leading to an immuno-mediated pathogenesis ...
Andrés, González-García   +1 more
openaire   +2 more sources

IMMUNOGENETICS OF GRAVES' OPHTHALMOPATHY

Clinical Endocrinology, 1988
SUMMARYWe have performed an immunogenetic analysis of 53 patients with severe Graves' ophthalmopathy, 51 patients with Graves' disease but little or no clinically apparent eye disease, and 90 controls. The distribution of restriction fragment length polymorphisms was analysed in the three groups, using probes for the HLA‐DQα and DRβ regions, the T‐cell
A P, Weetman   +5 more
openaire   +2 more sources

Graves ophthalmopathy

Current Opinion in Ophthalmology, 2001
Graves ophthalmopathy (GO) is an autoimmune disease that typically affects the thyroid gland and the orbit. The roles of the thyroid stimulating hormone receptor and cellular and humoral immunity in the pathogenesis of GO are being investigated. Investigators are gaining insights into the epidemiology of GO as it relates to other ocular and autoimmune ...
openaire   +2 more sources

Inducing Graves’ ophthalmopathy

Journal of Endocrinological Investigation, 2004
The majority of patients with Graves' disease (GD) have some degree of ocular involvement and this requires surgical or medical intervention in about 5% of cases. There are autoimmune and inflammatory processes operating in Graves' ophthalmopathy (GO), which together induce glycosaminoglycan production, edema and adipogenesis resulting in an increase ...
M, Ludgate, G, Baker
openaire   +2 more sources

Graves' ophthalmopathy

Medical Clinics of North America, 1995
Graves' ophthalmopathy is an organ-specific autoimmune process strongly linked to Graves' hyperthyroidism. Although the hyperthyroidism can be successfully treated, it is often the ophthalmopathy that produces the greatest long-term disability for patients suffering from this disease.
openaire   +2 more sources

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