Results 161 to 170 of about 225,446 (206)

Ciclosporine and Graves’ Ophthalmopathy

Hormone Research, 2008
The pharmacological treatment of Graves’ ophthalmopathy remains unsatisfactory due to the limited efficacy and severe side effects of the available drugs. Ciclosporine, an immunosuppressive drug has recently been used with the aim of controlling the autoimmune process considered to be responsible for the disease.
J P, Gayno, G, Strauch
openaire   +2 more sources

The Ophthalmopathy of Graves' Disease

Medical Clinics of North America, 1991
Fortunately, most patients with thyroid-related eye disease have mild ocular involvement that spontaneously involutes. Less than 5% of patients with hyperthyroidism will develop sufficiently severe ocular abnormalities that will require surgical intervention. Most patients with thyroid eye findings should be symptomatically managed.
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Introduction to Graves’ ophthalmopathy

2000
Although the pathogenesis of Graves’ ophthalmopathy is incompletely understood, we have a rather good insight as to how the pathologic changes in the orbit cause (in a mechanical way) the clinical characteristics. To better understand this it is important to be acquainted with the anatomy of the orbit.
Prummel, M.F., Koornneef, L., Mourits, M.P., Heufelder, A.E., Wiersinga, W.M.   +4 more
openaire   +2 more sources

Rationale of Treatment in Graves Ophthalmopathy

Plastic and Reconstructive Surgery, 2001
Graves ophthalmopathy is a chronic and multisystem disorder caused by an autoimmune process, characterized by the presence of antibodies that stimulate a general fibroblastic reaction (thyroid gland and lower extremities), and involves orbital fat tissue and muscles.
CLAUSER, Luigi, M. Galiè, E. Sarti, V. Dallera   +3 more
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Ophthalmopathy of Graves' Disease

New England Journal of Medicine, 1983
Soft-tissue swelling that would be innocuous in many locations has serious effects where local anatomy confines the swelling tissues within an inexpansible space. The anterior-tibial-compartment and carpal-tunnel syndromes are good examples of such conditions. The severe ophthalmopathy of Graves' disease is another.
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The Philosophy of Graves' Ophthalmopathy

Orbit, 2005
When asked what has been my philosophy of Graves' ophthalmopathy in the last 25 years in the process of caring for patients with this disease and doing clinical research, I identified in hindsight three major guiding principles. The first is a multidisciplinary approach to the disease.
openaire   +1 more source

Immunotherapy for Graves’ ophthalmopathy

Current Opinion in Endocrinology, Diabetes & Obesity, 2014
In recent years, immunosuppressive therapy, as an alternative to corticosteroids, has been proposed as novel agents which target the various antigens involved in the pathogenesis of Graves' ophthalmopathy. Although the lack of randomized and controlled studies suggests caution in generalizing results, some data show interesting results.Potential ...
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Immunosuppressive treatment of Graves' ophthalmopathy

Trends in Endocrinology & Metabolism, 1990
Steroids or orbital irradiation are effective in approximately 60% of patients with severe Graves' ophthalmopathy; the improvement of proptosis and extraocular muscle dysfunction, however, is limited. Better results are obtained by the combination of orbital irradiation and systemic steroids.
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Tocilizumab in Graves ophthalmopathy

Medicina Clínica (English Edition), 2020
Gemma, Garreta Fontelles, Cristina, Sangrador Pelluz, Josep Lluis, Macaya Pascual   +2 more
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The Role of Plasmapheresis in Graves' Ophthalmopathy

Experimental and Clinical Endocrinology & Diabetes, 2009
info:eu-repo/semantics ...
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