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The Ophthalmopathy of Graves' Disease
Annual Review of Medicine, 1992Ophthalmopathy is an integral component of Graves’ disease. It usually appears at the same time as hyperthyroidism, and is characterized by proptosis (exophthalmos), periorbital and conjunctival edema, eye muscle dysfunction, and on occasion corneal ulceration or optic neuropathy.
J A, Carter, R D, Utiger
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Prevention of Graves’ ophthalmopathy
Best Practice & Research Clinical Endocrinology & Metabolism, 2012Smoking is the most important risk factor for the occurrence/progression of Graves' ophthalmopathy (GO), as well as for its lower/slower response to immunosuppression. Accordingly, refrain from smoking should be urged, both as primary prevention (removal of risk factors in Graves' patients without GO), secondary prevention (early detection and ...
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THE MANAGEMENT OF Graves' OPHTHALMOPATHY
Clinical Endocrinology, 1989L'auteur decrit les differentes lesions de l'ophtalmopathie basedowienne et passe en revue les moyens therapeutiques disponibles: traitement chimique et chirurgical de l'affection thyroidienne, traitement immunosuppresseur, traitements antiinflammatoires locaux et correction chirurgicale.
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Canadian Medical Association journal, 1981
Graves' ophthalmopathy usually occurs in association with hyperthyroidism. Its occasional occurrence in the absence of thyroid disease suggests, however, that it may be a separate autoimmune disorder. While the evidence supporting an autoimmune pathogenesis is considerable for the ophthalmopathy, it is not so impressive as that for Graves ...
Wall, JR +3 more
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Graves' ophthalmopathy usually occurs in association with hyperthyroidism. Its occasional occurrence in the absence of thyroid disease suggests, however, that it may be a separate autoimmune disorder. While the evidence supporting an autoimmune pathogenesis is considerable for the ophthalmopathy, it is not so impressive as that for Graves ...
Wall, JR +3 more
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Ophthalmopathy of Graves' Disease
New England Journal of Medicine, 1983Soft-tissue swelling that would be innocuous in many locations has serious effects where local anatomy confines the swelling tissues within an inexpansible space. The anterior-tibial-compartment and carpal-tunnel syndromes are good examples of such conditions. The severe ophthalmopathy of Graves' disease is another.
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The Philosophy of Graves' Ophthalmopathy
Orbit, 2005When asked what has been my philosophy of Graves' ophthalmopathy in the last 25 years in the process of caring for patients with this disease and doing clinical research, I identified in hindsight three major guiding principles. The first is a multidisciplinary approach to the disease.
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Radiotherapy for Graves’ ophthalmopathy
2000The interest in the treatment of benign diseases with radiation therapy has grown particularly in the Western part of the world. In 1996, a questionnaire was sent to 1348 institutes worldwide listed in the directory of the Society for Therapeutic Radiology and Oncology asking whether the respondents considered a list of 28 most common benign disorders ...
Kahaly, G.J. +6 more
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The Ophthalmopathy of Graves' Disease
Medical Clinics of North America, 1991Fortunately, most patients with thyroid-related eye disease have mild ocular involvement that spontaneously involutes. Less than 5% of patients with hyperthyroidism will develop sufficiently severe ocular abnormalities that will require surgical intervention. Most patients with thyroid eye findings should be symptomatically managed.
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Immunotherapy for Graves’ ophthalmopathy
Current Opinion in Endocrinology, Diabetes & Obesity, 2014In recent years, immunosuppressive therapy, as an alternative to corticosteroids, has been proposed as novel agents which target the various antigens involved in the pathogenesis of Graves' ophthalmopathy. Although the lack of randomized and controlled studies suggests caution in generalizing results, some data show interesting results.Potential ...
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Rationale of Treatment in Graves Ophthalmopathy
Plastic and Reconstructive Surgery, 2001Graves ophthalmopathy is a chronic and multisystem disorder caused by an autoimmune process, characterized by the presence of antibodies that stimulate a general fibroblastic reaction (thyroid gland and lower extremities), and involves orbital fat tissue and muscles.
CLAUSER, Luigi +3 more
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