Results 41 to 50 of about 11,608,149 (298)
7 The role of biocatalysis in green and sustainable chemistry
, 2022 Biocatalysis is well recognized as a greener tool for organic synthesis with many successful ongoing industrial processes. Additionally, besides the research component, it can be used in outreach activities and the Chemistry and Chemical Engineering ...
Iris S. Teixeira +7 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Visible-light photoredox-catalyzed umpolung carboxylation of carbonyl compounds with CO2
Nature Communications, 2021 Compounds bearing a carbonyl group, such as aldehydes and ketones, are important industrial chemicals and widespread in pharmaceuticals and natural products.
Guang-Mei Cao +7 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Completing Our Education. Green Chemistry in the Curriculum [PDF]
Journal of Chemical Education, 2006 This Commentary resulted from a series of conversations between an international group of chemistry and chemical engineering graduate students from the 3rd Annual ACS Green Chemistry Summer School, who reflected on their undergraduate education and discussed 1) the areas of green chemistry that were often neglected, 2) the value of integrating green ...
Braun, B +7 more
openaire +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Nickel-catalyzed electrochemical carboxylation of unactivated aryl and alkyl halides with CO2
Nature Communications, 2021 Electrochemistry is a promising approach to make existing chemical protocols milder, but many simple transformations of feedstocks are still out of reach.
Guo-Quan Sun +7 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
C3 Selective chalcogenation and fluorination of pyridine using classic Zincke imine intermediates
Nature CommunicationsRegioselective C–H functionalization of pyridines remains a persistent challenge due to their inherent electronically deficient properties. In this report, we present a strategy for the selective pyridine C3-H thiolation, selenylation, and fluorination ...
Shun Li +12 more
doaj +1 more source
Facilitating the transition to sustainable green chemistry [PDF]
, 2018 Sustainable green chemistry depends on technically feasible, cost-effective and socially acceptable decisions by regulators, industry and the wider community. The discipline needs to embrace a new suite of tools and train proponents in their use.
Karen Makuch +9 more
core +1 more source