Results 51 to 60 of about 12,534,618 (262)

Skeletal editing of pyridines to aryldialdehydes

Nature Communications
Electron-deficient nitrogen-containing aromatic heterocycles, particularly pyridine derivatives, can be converted into all-carbon aromatic frameworks via the ANRORC (Addition of Nucleophile, Ring-Opening, and Ring-Closing) skeletal editing process ...
Meixin Yan, Yonglin Shi, Cong Lv, Shunyao Huang, Shun Li, Dexi Yang, Jiangui Zhao, Zhishan Su, Weidong Jiang, Weichao Xue, Jiaqi Xu, Xueli Zheng, Ruixiang Li, Hua Chen, Haiyan Fu   +14 more
doaj   +1 more source

Arylcarboxylation of unactivated alkenes with CO2 via visible-light photoredox catalysis

Nature Communications, 2023
Photocatalytic carboxylation of alkenes with CO2 is a promising and sustainable strategy to synthesize high value-added carboxylic acids. However, it is challenging and rarely investigated for unactivated alkenes due to their low reactivities. Herein, we
Wei Zhang, Zhen Chen, Yuan-Xu Jiang, Li-Li Liao, Wei Wang, Jian-Heng Ye, Da-Gang Yu   +6 more
doaj   +1 more source

Erratum: Efficient separation of immiscible oil/water mixtures using a perforated lotus leaf (Green Chemistry (2019) 21 (6579-6584) DOI: 10.1039/C9GC03254A)

, 2020
The authors regret that Fig. 2 and 3 are incorrect. The correct figures are as follows: (Figure Presented) The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
Xu, Zhe, Zhang, Yuheng, Yu, Cunming, Zhang, Chunhui, Xiao, Xiao, Liu, Guoliang, Ras, Robin H.A., Wang, Bing, Jiang, Lei   +8 more
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Skeletal editing of 4-arylpyrimidines into diverse nitrogen heteroaromatics via four-atom synthons

Nature Communications
Scaffold hopping is a key strategy in drug discovery. While one-to-one scaffold hopping strategies are thriving and evolving, one-to-multiple strategies remain challenging to design.
Shun Li, Yonglin Shi, Juan Tang, Meixin Yan, Shunyao Huang, Tingying Dou, Shenxiang Wang, Xinchao Jin, Zhishan Su, Weidong Jiang, Jiaqi Xu, Xueli Zheng, Ruixiang Li, Hua Chen, Weichao Xue, Haiyan Fu   +15 more
doaj   +1 more source

Magnetic COFs as satisfied support for lipase immobilization and recovery to effectively achieve the production of biodiesel by great maintenance of enzyme activity

Biotechnology for Biofuels, 2021
Background Production of biodiesel from renewable sources such as inedible vegetable oils by enzymatic catalysis has been a hotspot but remains a challenge on the efficient use of an enzyme.
Zi-Wen Zhou, Chun-Xian Cai, Xiu Xing, Jun Li, Zu-E. Hu, Zong-Bo Xie, Na Wang, Xiao-Qi Yu   +7 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Asymmetric synthesis of tetrazole and dihydroisoquinoline derivatives by isocyanide-based multicomponent reactions

Nature Communications, 2019
Asymmetric isocyanide-based multicomponent reactions are elegant, yet challenging, strategies to access valuable N-heterocycles. Here, the authors employ a chiral Mg(II) -N,N′-dioxide catalyst in three- or four-component reactions to obtain chiral ...
Qian Xiong, Shunxi Dong, Yushuang Chen, Xiaohua Liu, Xiaoming Feng   +4 more
doaj   +1 more source

Green Chemistry for Postgraduates

Educación Química, 2018
Química verde para posgraduados The multidisciplinary nature of Green Chemistry is recognised worldwide as a route to the development of chemical products and processes with lower environmental impact.
Louise Summerton, Andrew J. Hunt, James H. Clark   +2 more
doaj   +1 more source