Results 61 to 70 of about 11,608,149 (298)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Nature Communications, 2019 Asymmetric isocyanide-based multicomponent reactions are elegant, yet challenging, strategies to access valuable N-heterocycles. Here, the authors employ a chiral Mg(II) -N,N′-dioxide catalyst in three- or four-component reactions to obtain chiral ...
Qian Xiong +4 more
doaj +1 more source
Green Chemistry for Postgraduates
Educación Química, 2018 Química verde para posgraduados The multidisciplinary nature of Green Chemistry is recognised worldwide as a route to the development of chemical products and processes with lower environmental impact.
Louise Summerton +2 more
doaj +1 more source
The effect of green chemistry education based on practical activity on learning and attitude of pre-service chemistry teachers [PDF]
Fanāvarī-i āmūzish, 2018 Background and Objective:Chemistry plays a fundamental role in human civilization and its place in economics, politics and life is becoming more and more prominent and covers a wide range of chemical products such as drugs, dyes, fertilizers, etc ...
S. Mirzaei +2 more
doaj +1 more source
The chemistry of education : a periodic relationship [PDF]
, 2003 xiii, 312 leaves ; 28 cm.The purpose and focus of this research is to examine a chemistry of education and to build a metacognitive bridge between the two disciplines, chemistry and education, through autobiographical narrative development of a ...
H-Duke, Michelle +1 more
core
Experimental work in science education from green chemistry perspectives
, 2021 Experimental work is an important component of science subjects at all educational levels. The implication of green chemistry ideas indicated the need for optimization of traditional experimental work by implementing green chemistry principles to promote
Vesna Ferk Savec +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
An isolable phosphaalumene(3) capable of small molecule activation via unique modes of reactivity
Nature CommunicationsThe chemistry of phosphaalumenes [R–Al=P–R’] featuring multiple bonds between phosphorus and aluminum remains largely unexplored. Here we show the syntheses of a phosphaalumene(3) through either the reaction of DippNacNacM (DippNacNac = HC[(CMe)N(2,6- i ...
Yan Cha +8 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Nature Communications, 2019 Phosphonyl and carboxyl groups are valuable functional groups, however their simultaneous incorporation via catalytic difunctionalization of alkenes has not been realized yet.
Qiang Fu +6 more
doaj +1 more source