Results 51 to 60 of about 505,963 (341)
Sea as a color palette: the ecology and evolution of fluorescence
Zoological Letters, 2020 Fluorescence and luminescence are widespread optical phenomena exhibited by organisms living in terrestrial and aquatic environments. While many underlying mechanistic features have been identified and characterized at the molecular and cellular levels ...
Marie-Lyne Macel +5 more
doaj +1 more source
Visible Light-Activated Photosensitization of Hybridization of Far-red Fluorescent Protein and Silk [PDF]
, 2018 Fluorescent proteins often result in phototoxicity and cytotoxicity, in particular because some red fluorescent proteins (RFP) produce and release reactive oxygen species (ROS). The photogeneration of ROS is considered as a detrimental side effect in cellular imaging or is proactively utilized for ablating cancerous tissue.
arxiv +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
RNA Mimics of Green Fluorescent Protein [PDF]
Science, 2011 Selection for RNAs that bind and activate derivatives of the green fluorescent protein fluorophore yields a wide range of useful spectral properties.
Karen Y. Wu +2 more
openaire +3 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
A family of GFP-like proteins with different spectral properties in lancelet
Biology Direct, 2008 Background Members of the green fluorescent protein (GFP) family share sequence similarity and the 11-stranded β-barrel fold. Fluorescence or bright coloration, observed in many members of this family, is enabled by the intrinsic properties of the ...
Mushegian Arcady +6 more
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Green fluorescent protein [PDF]
Nature Chemistry, 2008 The 2008 Nobel Prize for Chemistry has been awarded to Osamu Shimomura, Martin Chalfie and Roger Tsien for the discovery and development of the so-called green fluorescent ...
openaire +2 more sources
Selective Immobilization of Fluorescent Proteins for the Fabrication of Photoactive Materials
Molecules, 2019 The immobilization of fluorescent proteins is a key technology enabling to fabricate a new generation of photoactive materials with potential technological applications. Herein we have exploited superfolder green (sGFP) and red (RFP) fluorescent proteins
Ana I. Benítez-Mateos +5 more
doaj +1 more source
Dynamics of Natural Killer cell receptor revealed by quantitative analysis of photoswitchable protein [PDF]
Biophysical Journal, Volume 105, 1-10, (2013), 2013 Natural Killer (NK) cell activation is dynamically regulated by numerous activating and inhibitory surface receptors that accumulate at the immune synapse. Quantitative analysis of receptor dynamics has been limited by methodologies which rely on indirect measurements such as fluorescence recovery after photobleaching.
arxiv +1 more source