Results 241 to 250 of about 162,324 (292)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Bionic Solar‐Powered Heavy Metal Trap for Eco‐Friendly Sludge Drying and Simultaneous Electricity Generation

open access: yesAdvanced Science, EarlyView.
Herein, we propose a solar‐powered heavy metal trap (SPHT) for sludge disposal. The indoor experiments demonstrated that the sludge water content decreased from 90 % to 31 %, coupled with a decrease in heavy metal content to 6 % at most. Furthermore, the designed SPHT generated an initial potential of 0.10 V, and monitoring this hydrovoltaic potential ...
Yanlin Li   +7 more
wiley   +1 more source

Barriers to the Implementation of Iran's Clean Air Act: A Policy-Oriented Scoping Review. [PDF]

open access: yesEnviron Health Insights
Bouzarjomehri H   +7 more
europepmc   +1 more source

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

open access: yesAdvanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang   +10 more
wiley   +1 more source

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang   +10 more
wiley   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang   +11 more
wiley   +1 more source

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